NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Frostburg | 59 | 113 | Towson (131) | Final | W | 54 |
| 2 | 2021-11-12 | Florida (55) | 70 | 87 | Towson (199) | Final | W | 17 |
| 3 | 2021-11-14 | Towson (131) | 64 | 48 | Wofford (228) | Final | W | 16 |
| 4 | 2021-11-15 | Towson (131) | 52 | 100 | North Carolina State (7) | Final | L | -48 |
| 5 | 2021-11-23 | Millersville | 46 | 95 | Towson (199) | Final | W | 49 |
| 6 | 2021-11-27 | Howard (285) | 52 | 96 | Towson (94) | Final | W | 44 |
| 7 | 2021-11-29 | Delaware State (354) | 47 | 76 | Towson (94) | Final | W | 29 |
| 8 | 2021-12-04 | Towson (199) | 66 | 51 | East Carolina (106) | Final | W | 15 |
| 9 | 2021-12-08 | Towson (53) | 70 | 56 | UMass-Lowell (225) | Final | W | 14 |
| 10 | 2021-12-11 | Towson (53) | 79 | 61 | American (132) | Final | W | 18 |
| 11 | 2021-12-14 | Memphis (97) | 0 | 0 | Towson (35) | Cancelled | - | - |
| 12 | 2021-12-22 | Towson (41) | 0 | 0 | Penn State (111) | Cancelled | - | - |
| 13 | 2021-12-31 | Towson (199) | 0 | 0 | Drexel (168) | Postponed | - | - |
| 14 | 2022-01-02 | Towson (199) | 0 | 0 | Delaware (241) | Postponed | - | - |
| 15 | 2022-01-04 | Towson (44) | 0 | 0 | Seton Hall (109) | Canceled | - | - |
| 16 | 2022-01-07 | Elon (62) | 54 | 66 | Towson (44) | Final | W | 12 |
| 17 | 2022-01-09 | William & Mary (210) | 55 | 91 | Towson (199) | Final | W | 36 |
| 18 | 2022-01-12 | Towson (199) | 54 | 68 | Princeton (28) | Final | L | -14 |
| 19 | 2022-01-16 | James Madison (48) | 70 | 79 | Towson (199) | Final | W | 9 |
| 20 | 2022-01-18 | Towson (45) | 54 | 58 | Drexel (83) | Final | L | -4 |
| 21 | 2022-01-21 | Towson (45) | 72 | 88 | Charleston (180) | Final | L | -16 |
| 22 | 2022-01-23 | Towson (199) | 72 | 49 | UNC-Wilmington (324) | Final | W | 23 |
| 23 | 2022-01-28 | Northeastern (149) | 81 | 86 | Towson (68) | Final | W | 5 |
| 24 | 2022-01-30 | Hofstra (307) | 45 | 86 | Towson (68) | Final | W | 41 |
| 25 | 2022-02-04 | Towson (67) | 76 | 60 | William & Mary (280) | Final | W | 16 |
| 26 | 2022-02-06 | Towson (67) | 67 | 52 | Elon (131) | Final | W | 15 |
| 27 | 2022-02-09 | Delaware (241) | 81 | 78 | Towson (199) | Final | L | -3 |
| 28 | 2022-02-13 | Towson (65) | 87 | 67 | James Madison (157) | Final | W | 20 |
| 29 | 2022-02-18 | UNC-Wilmington (329) | 51 | 67 | Towson (66) | Final | W | 16 |
| 30 | 2022-02-20 | Charleston (179) | 57 | 84 | Towson (66) | Final | W | 27 |
| 31 | 2022-02-25 | Towson (199) | 73 | 50 | Hofstra (263) | Final | W | 23 |
| 32 | 2022-02-27 | Towson (63) | 57 | 56 | Northeastern (187) | Final | W | 1 |
| 33 | 2022-03-03 | Delaware (77) | 85 | 71 | Towson (64) | Final | L | -14 |
| 34 | 2022-03-05 | Drexel (58) | 61 | 69 | Towson (64) | Final | W | 8 |
| 35 | 2022-03-11 | Northeastern (180) | 49 | 58 | Towson (69) | Final | W | 9 |
| 36 | 2022-03-12 | Towson (69) | 55 | 56 | Delaware (77) | Final | L | -1 |
| 37 | 2022-03-18 | Old Dominion (94) | 72 | 66 | Towson (69) | Final | L | -6 |