NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Mount St Mary's (111) | 68 | 81 | Seton Hall (66) | Final | W | 13 |
| 2 | 2021-11-13 | Fordham (83) | 82 | 63 | Seton Hall (66) | Final | L | -19 |
| 3 | 2021-11-16 | Lehigh (103) | 77 | 87 | Seton Hall (141) | Final | W | 10 |
| 4 | 2021-11-25 | Iowa | Seton Hall | Cancelled | - | - | ||
| 5 | 2021-11-25 | USC (25) | 79 | 65 | Seton Hall (70) | Final | L | -14 |
| 6 | 2021-11-26 | Toledo (166) | 63 | 68 | Seton Hall (70) | Final/OT | W | 5 |
| 7 | 2021-12-01 | Iona (245) | 0 | 0 | Seton Hall (125) | Postponed | - | - |
| 8 | 2021-12-03 | Connecticut (12) | 74 | 49 | Seton Hall (125) | Final | L | -25 |
| 9 | 2021-12-05 | Seton Hall (125) | 75 | 88 | St. John's (145) | Final | L | -13 |
| 10 | 2021-12-11 | Seton Hall (152) | 70 | 60 | Princeton (45) | Final | W | 10 |
| 11 | 2021-12-14 | Central Florida (22) | 68 | 56 | Seton Hall (129) | Final | L | -12 |
| 12 | 2021-12-19 | Marquette (83) | 57 | 69 | Seton Hall (70) | Final | W | 12 |
| 13 | 2021-12-21 | Wagner (152) | 62 | 70 | Seton Hall (105) | Final | W | 8 |
| 14 | 2021-12-31 | Seton Hall (70) | 73 | 76 | Villanova (35) | Final | L | -3 |
| 15 | 2022-01-02 | Seton Hall (70) | 0 | 0 | Georgetown (119) | Postponed | - | - |
| 16 | 2022-01-04 | Towson (44) | 0 | 0 | Seton Hall (109) | Canceled | - | - |
| 17 | 2022-01-07 | Butler (320) | 0 | 0 | Seton Hall (109) | Postponed | - | - |
| 18 | 2022-01-09 | Xavier (190) | 0 | 0 | Seton Hall (70) | Postponed | - | - |
| 19 | 2022-01-14 | Seton Hall (108) | 60 | 83 | Creighton (40) | Final | L | -23 |
| 20 | 2022-01-16 | Seton Hall (70) | 62 | 42 | Providence (147) | Final | W | 20 |
| 21 | 2022-01-19 | St. John's (87) | 79 | 84 | Seton Hall (70) | Final | W | 5 |
| 22 | 2022-01-21 | Seton Hall (101) | 38 | 71 | Connecticut (18) | Final | L | -33 |
| 23 | 2022-01-26 | Seton Hall (95) | 43 | 62 | Marquette (66) | Final | L | -19 |
| 24 | 2022-01-30 | DePaul (39) | 85 | 65 | Seton Hall (95) | Final | L | -20 |
| 25 | 2022-02-02 | Georgetown (216) | 62 | 91 | Seton Hall (105) | Final | W | 29 |
| 26 | 2022-02-04 | Xavier (230) | 86 | 91 | Seton Hall (105) | Final | W | 5 |
| 27 | 2022-02-06 | Seton Hall (105) | 72 | 56 | Butler (329) | Final | W | 16 |
| 28 | 2022-02-09 | Seton Hall (70) | 60 | 50 | Georgetown (119) | Final | W | 10 |
| 29 | 2022-02-13 | Villanova (64) | 60 | 72 | Seton Hall (94) | Final | W | 12 |
| 30 | 2022-02-18 | Providence (159) | 52 | 62 | Seton Hall (85) | Final | W | 10 |
| 31 | 2022-02-20 | Creighton (39) | 97 | 91 | Seton Hall (85) | Final/2OT | L | -6 |
| 32 | 2022-02-22 | Butler (336) | 55 | 84 | Seton Hall (86) | Final | W | 29 |
| 33 | 2022-02-25 | Seton Hall (70) | 94 | 90 | DePaul (229) | Final | W | 4 |
| 34 | 2022-03-01 | Seton Hall (79) | 74 | 53 | Xavier (244) | Final | W | 21 |
| 35 | 2022-03-04 | Butler (337) | 39 | 58 | Seton Hall (79) | Final | W | 19 |
| 36 | 2022-03-05 | Seton Hall (79) | 66 | 65 | Creighton (39) | Final | W | 1 |
| 37 | 2022-03-06 | Seton Hall (79) | 55 | 64 | Villanova (57) | Final | L | -9 |
| 38 | 2022-03-12 | Seton Hall | Stony Brook | TBD | - | - | ||
| 39 | 2022-03-17 | Fairleigh Dickinson (228) | 45 | 67 | Seton Hall (77) | Final | W | 22 |
| 40 | 2022-03-21 | Virginia Commonwealth (88) | 67 | 70 | Seton Hall (77) | Final | W | 3 |
| 41 | 2022-03-24 | Drexel (68) | 71 | 78 | Seton Hall (77) | Final | W | 7 |
| 42 | 2022-03-28 | Seton Hall (77) | 78 | 75 | Columbia (74) | Final | W | 3 |
| 43 | 2022-03-31 | Seton Hall (77) | 74 | 73 | Middle Tennessee (71) | Final | W | 1 |
| 44 | 2022-04-02 | Seton Hall (77) | 50 | 82 | South Dakota State (53) | Final | L | -32 |