NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Virginia (264) | 69 | 84 | James Madison (114) | Final | W | 15 |
| 2 | 2021-11-14 | Maryland (5) | 81 | 45 | James Madison (114) | Final | L | -36 |
| 3 | 2021-11-18 | James Madison (48) | 61 | 66 | Liberty (144) | Final/OT | L | -5 |
| 4 | 2021-11-21 | Hampton (277) | 60 | 78 | James Madison (185) | Final | W | 18 |
| 5 | 2021-11-24 | North Carolina Central (338) | 54 | 77 | James Madison (168) | Final | W | 23 |
| 6 | 2021-11-27 | James Madison (168) | 45 | 62 | Buffalo (101) | Final | L | -17 |
| 7 | 2021-12-02 | James Madison (182) | 50 | 54 | George Washington (104) | Final | L | -4 |
| 8 | 2021-12-05 | James Madison (182) | 47 | 93 | North Carolina (7) | Final | L | -46 |
| 9 | 2021-12-09 | Villanova (178) | 76 | 67 | James Madison (179) | Final | L | -9 |
| 10 | 2021-12-12 | West Virginia (73) | 75 | 68 | James Madison (179) | Final/OT | L | -7 |
| 11 | 2021-12-20 | James Madison (196) | 69 | 61 | George Mason (190) | Final | W | 8 |
| 12 | 2021-12-31 | James Madison (48) | 0 | 0 | Delaware (241) | Postponed | - | - |
| 13 | 2022-01-02 | James Madison (48) | 0 | 0 | Drexel (168) | Postponed | - | - |
| 14 | 2022-01-07 | William & Mary (254) | 39 | 67 | James Madison (176) | Final | W | 28 |
| 15 | 2022-01-09 | Elon (233) | 57 | 59 | James Madison (48) | Final | W | 2 |
| 16 | 2022-01-16 | James Madison (48) | 70 | 79 | Towson (199) | Final | L | -9 |
| 17 | 2022-01-18 | James Madison (146) | 57 | 64 | Delaware (108) | Final | L | -7 |
| 18 | 2022-01-21 | James Madison (146) | 57 | 56 | UNC-Wilmington (320) | Final | W | 1 |
| 19 | 2022-01-23 | James Madison (48) | 64 | 55 | Charleston (90) | Final | W | 9 |
| 20 | 2022-01-28 | Hofstra (307) | 53 | 65 | James Madison (159) | Final | W | 12 |
| 21 | 2022-01-30 | Northeastern (149) | 62 | 50 | James Madison (159) | Final | L | -12 |
| 22 | 2022-02-04 | James Madison (166) | 71 | 56 | Elon (131) | Final | W | 15 |
| 23 | 2022-02-06 | James Madison (166) | 64 | 58 | William & Mary (280) | Final | W | 6 |
| 24 | 2022-02-13 | Towson (65) | 87 | 67 | James Madison (157) | Final | L | -20 |
| 25 | 2022-02-16 | James Madison (48) | 61 | 64 | Drexel (168) | Final | L | -3 |
| 26 | 2022-02-18 | Charleston (179) | 71 | 69 | James Madison (155) | Final | L | -2 |
| 27 | 2022-02-20 | UNC-Wilmington (329) | 51 | 73 | James Madison (155) | Final | W | 22 |
| 28 | 2022-02-25 | James Madison (48) | 52 | 65 | Northeastern (307) | Final | L | -13 |
| 29 | 2022-02-27 | James Madison (159) | 68 | 63 | Hofstra (294) | Final | W | 5 |
| 30 | 2022-03-03 | Drexel (58) | 80 | 60 | James Madison (169) | Final | L | -20 |
| 31 | 2022-03-05 | Delaware (77) | 62 | 78 | James Madison (169) | Final | W | 16 |