NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-10 | Hofstra (211) | 41 | 70 | Albany (241) | Final | L | -29 |
| 2 | 2021-11-17 | Molloy | 51 | 52 | Hofstra (269) | Final | W | 1 |
| 3 | 2021-11-20 | Loyola-Maryland (267) | 53 | 55 | Hofstra (269) | Final | W | 2 |
| 4 | 2021-11-24 | Hofstra (276) | 32 | 65 | Georgia Tech (82) | Final | L | -33 |
| 5 | 2021-11-26 | Hofstra (263) | 72 | 57 | Kennesaw State (246) | Final | W | 15 |
| 6 | 2021-12-04 | Hofstra (263) | 62 | 64 | Howard (116) | Final/OT | L | -2 |
| 7 | 2021-12-06 | Hofstra (267) | 46 | 58 | Morgan State (270) | Final | L | -12 |
| 8 | 2021-12-11 | Ole Miss (47) | 59 | 37 | Hofstra (276) | Final | L | -22 |
| 9 | 2021-12-18 | Hofstra | Cleveland State | Cancelled | - | - | ||
| 10 | 2021-12-21 | Stony Brook (43) | 0 | 0 | Hofstra (283) | Cancelled | - | - |
| 11 | 2021-12-28 | Hofstra (263) | 0 | 0 | Columbia (44) | Cancelled | - | - |
| 12 | 2021-12-31 | UNC-Wilmington (324) | 0 | 0 | Hofstra (263) | Postponed | - | - |
| 13 | 2022-01-02 | Charleston (90) | 0 | 0 | Hofstra (263) | Postponed | - | - |
| 14 | 2022-01-09 | Hofstra (263) | 51 | 64 | Northeastern (307) | Final | L | -13 |
| 15 | 2022-01-14 | Hofstra (287) | 38 | 73 | Delaware (128) | Final | L | -35 |
| 16 | 2022-01-16 | Hofstra (263) | 53 | 72 | Drexel (168) | Final | L | -19 |
| 17 | 2022-01-21 | William & Mary (274) | 56 | 48 | Hofstra (294) | Final | L | -8 |
| 18 | 2022-01-23 | Elon (233) | 62 | 58 | Hofstra (263) | Final | L | -4 |
| 19 | 2022-01-28 | Hofstra (307) | 53 | 65 | James Madison (159) | Final | L | -12 |
| 20 | 2022-01-30 | Hofstra (307) | 45 | 86 | Towson (68) | Final | L | -41 |
| 21 | 2022-02-01 | UNC-Wilmington (321) | 40 | 56 | Hofstra (310) | Final | W | 16 |
| 22 | 2022-02-06 | Northeastern (126) | 43 | 56 | Hofstra (310) | Final | W | 13 |
| 23 | 2022-02-11 | Drexel (74) | 63 | 47 | Hofstra (289) | Final | L | -16 |
| 24 | 2022-02-13 | Delaware (90) | 71 | 58 | Hofstra (289) | Final | L | -13 |
| 25 | 2022-02-18 | Hofstra (287) | 53 | 66 | Elon (143) | Final | L | -13 |
| 26 | 2022-02-20 | Hofstra (287) | 48 | 61 | William & Mary (278) | Final | L | -13 |
| 27 | 2022-02-23 | Charleston (174) | 61 | 73 | Hofstra (294) | Final | W | 12 |
| 28 | 2022-02-25 | Towson (199) | 73 | 50 | Hofstra (263) | Final | L | -23 |
| 29 | 2022-02-27 | James Madison (159) | 68 | 63 | Hofstra (294) | Final | L | -5 |
| 30 | 2022-03-03 | Hofstra (286) | 35 | 75 | Charleston (186) | Final | L | -40 |
| 31 | 2022-03-05 | Hofstra (286) | 67 | 52 | UNC-Wilmington (334) | Final | W | 15 |
| 32 | 2022-03-10 | UNC-Wilmington (336) | 45 | 46 | Hofstra (287) | Final | W | 1 |
| 33 | 2022-03-11 | Hofstra (287) | 39 | 60 | Drexel (64) | Final | L | -21 |