NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-11 | Hawaii (134) | 50 | 90 | USC (25) | Final | W | 40 |
| 2 | 2021-11-14 | USC (91) | 65 | 48 | Virginia (264) | Final | W | 17 |
| 3 | 2021-11-18 | Western Michigan (281) | 50 | 80 | USC (25) | Final | W | 30 |
| 4 | 2021-11-20 | Missouri State (33) | 67 | 41 | USC (68) | Final | L | -26 |
| 5 | 2021-11-25 | USC (25) | 79 | 65 | Seton Hall (70) | Final | W | 14 |
| 6 | 2021-11-26 | Iowa (9) | 0 | 0 | USC (25) | Cancelled | - | - |
| 7 | 2021-11-27 | USC (87) | 47 | 56 | Central Florida (64) | Final | L | -9 |
| 8 | 2021-12-02 | UC-Irvine (151) | 69 | 78 | USC (70) | Final | W | 9 |
| 9 | 2021-12-05 | San Francisco (159) | 78 | 63 | USC (70) | Final | L | -15 |
| 10 | 2021-12-15 | Cal State-Northridge (245) | 51 | 76 | USC (82) | Final | W | 25 |
| 11 | 2021-12-18 | Texas Southern (337) | 45 | 77 | USC (25) | Final | W | 32 |
| 12 | 2021-12-21 | USC (75) | 0 | 0 | Long Beach State (60) | Cancelled | - | - |
| 13 | 2021-12-31 | Arizona (123) | 0 | 0 | USC (25) | Postponed | - | - |
| 14 | 2022-01-02 | Arizona State (46) | 0 | 0 | USC (25) | Postponed | - | - |
| 15 | 2022-01-07 | USC (70) | 58 | 71 | Colorado (17) | Final | L | -13 |
| 16 | 2022-01-09 | Arizona (123) | 67 | 76 | USC (25) | Final | W | 9 |
| 17 | 2022-01-09 | USC | Utah | Postponed | - | - | ||
| 18 | 2022-01-14 | Washington State (56) | 71 | 63 | USC (53) | Final | L | -8 |
| 19 | 2022-01-16 | Washington (23) | 66 | 73 | USC (25) | Final | W | 7 |
| 20 | 2022-01-20 | USC (61) | 43 | 66 | UCLA (71) | Final | L | -23 |
| 21 | 2022-01-23 | UCLA (1) | 68 | 58 | USC (25) | Final | L | -10 |
| 22 | 2022-01-28 | USC (81) | 61 | 63 | Oregon State (50) | Final/OT | L | -2 |
| 23 | 2022-01-30 | USC (81) | 48 | 80 | Oregon (23) | Final | L | -32 |
| 24 | 2022-02-04 | California (85) | 62 | 59 | USC (90) | Final | L | -3 |
| 25 | 2022-02-06 | Stanford (3) | 83 | 57 | USC (90) | Final | L | -26 |
| 26 | 2022-02-09 | USC (25) | 69 | 91 | Utah (61) | Final | L | -22 |
| 27 | 2022-02-11 | USC (95) | 70 | 59 | Washington (141) | Final | W | 11 |
| 28 | 2022-02-13 | USC (95) | 54 | 57 | Washington State (48) | Final | L | -3 |
| 29 | 2022-02-18 | Utah (36) | 62 | 83 | USC (101) | Final | W | 21 |
| 30 | 2022-02-20 | Colorado (40) | 67 | 54 | USC (101) | Final | L | -13 |
| 31 | 2022-02-24 | USC (89) | 60 | 58 | Arizona State (65) | Final | W | 2 |
| 32 | 2022-02-26 | USC (89) | 59 | 68 | Arizona (18) | Final | L | -9 |
| 33 | 2022-03-02 | USC (84) | 60 | 73 | UCLA (62) | Final | L | -13 |