NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | East Stroudsburg | 35 | 82 | Lehigh (67) | Final | W | 47 |
| 2 | 2021-11-12 | Saint Peter's (340) | 68 | 84 | Lehigh (189) | Final | W | 16 |
| 3 | 2021-11-16 | Lehigh (103) | 77 | 87 | Seton Hall (141) | Final | L | -10 |
| 4 | 2021-11-19 | Mount St Mary's (214) | 72 | 91 | Lehigh (103) | Final | W | 19 |
| 5 | 2021-11-21 | Merrimack (348) | 64 | 85 | Lehigh (103) | Final | W | 21 |
| 6 | 2021-11-27 | Rider (336) | 44 | 69 | Lehigh (107) | Final | W | 25 |
| 7 | 2021-11-28 | Missouri (49) | 88 | 67 | Lehigh (107) | Final | L | -21 |
| 8 | 2021-12-01 | Lehigh (130) | 60 | 65 | Villanova (166) | Final | L | -5 |
| 9 | 2021-12-04 | Binghamton (165) | 68 | 79 | Lehigh (189) | Final | W | 11 |
| 10 | 2021-12-18 | Delaware State (348) | 39 | 82 | Lehigh (189) | Final | W | 43 |
| 11 | 2021-12-21 | Lehigh (143) | 70 | 57 | George Washington (134) | Final | W | 13 |
| 12 | 2021-12-30 | American (137) | 0 | 0 | Lehigh (125) | Postponed | - | - |
| 13 | 2022-01-02 | Lehigh (189) | 72 | 52 | Colgate (319) | Final | W | 20 |
| 14 | 2022-01-05 | Army (109) | 55 | 62 | Lehigh (189) | Final | W | 7 |
| 15 | 2022-01-08 | Lehigh (189) | 53 | 64 | Holy Cross (121) | Final | L | -11 |
| 16 | 2022-01-12 | Bucknell (275) | 56 | 45 | Lehigh (189) | Final | L | -11 |
| 17 | 2022-01-15 | Lehigh (123) | 72 | 61 | Loyola-Maryland (299) | Final | W | 11 |
| 18 | 2022-01-19 | Navy (127) | 65 | 99 | Lehigh (189) | Final | W | 34 |
| 19 | 2022-01-22 | Boston University (149) | 67 | 79 | Lehigh (139) | Final | W | 12 |
| 20 | 2022-01-26 | Lehigh (122) | 57 | 70 | Army (233) | Final | L | -13 |
| 21 | 2022-01-28 | Holy Cross (142) | 61 | 67 | Lehigh (122) | Final | W | 6 |
| 22 | 2022-02-05 | Lehigh (189) | 68 | 65 | Boston University (284) | Final | W | 3 |
| 23 | 2022-02-09 | Colgate (319) | 56 | 72 | Lehigh (189) | Final | W | 16 |
| 24 | 2022-02-12 | Lehigh (116) | 76 | 52 | Lafayette (281) | Final | W | 24 |
| 25 | 2022-02-16 | Lehigh (189) | 54 | 56 | Bucknell (275) | Final | L | -2 |
| 26 | 2022-02-19 | Loyola-Maryland (317) | 49 | 73 | Lehigh (113) | Final | W | 24 |
| 27 | 2022-02-22 | Lehigh (118) | 45 | 64 | American (163) | Final | L | -19 |
| 28 | 2022-02-23 | Lehigh (118) | 52 | 61 | American (163) | Final | L | -9 |
| 29 | 2022-02-26 | Lafayette (273) | 65 | 61 | Lehigh (118) | Final | L | -4 |
| 30 | 2022-03-02 | Lehigh (148) | 64 | 42 | Navy (290) | Final | W | 22 |
| 31 | 2022-03-07 | Lehigh (148) | 53 | 56 | Bucknell (108) | Final | L | -3 |