NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Mount St Mary's (111) | 68 | 81 | Seton Hall (66) | Final | L | -13 |
| 2 | 2021-11-13 | Valley Forge | 15 | 102 | Mount St Mary's (111) | Final | W | 87 |
| 3 | 2021-11-16 | Mount St Mary's (214) | 57 | 98 | Maryland (15) | Final | L | -41 |
| 4 | 2021-11-19 | Mount St Mary's (214) | 72 | 91 | Lehigh (103) | Final | L | -19 |
| 5 | 2021-11-23 | Howard (116) | 56 | 49 | Mount St Mary's (270) | Final | L | -7 |
| 6 | 2021-11-28 | Mount St Mary's (245) | 59 | 83 | Clemson (100) | Final | L | -24 |
| 7 | 2021-12-04 | Mount St Mary's (270) | 55 | 56 | Loyola-Maryland (258) | Final | L | -1 |
| 8 | 2021-12-07 | Mount St Mary's (318) | 50 | 94 | Ohio State (36) | Final | L | -44 |
| 9 | 2021-12-18 | Maryland-Eastern Shore (219) | 65 | 82 | Mount St Mary's (270) | Final | W | 17 |
| 10 | 2021-12-21 | UMBC (346) | 0 | 0 | Mount St Mary's (295) | Cancelled | - | - |
| 11 | 2021-12-29 | Mount St Mary's (295) | 0 | 0 | Fairleigh Dickinson (261) | Forfeit | - | - |
| 12 | 2021-12-31 | Mount St Mary's (270) | 0 | 2 | Wagner (327) | Forfeit | L | -2 |
| 13 | 2022-01-06 | Long Island (336) | 54 | 70 | Mount St Mary's (298) | Final | W | 16 |
| 14 | 2022-01-08 | St. Francis (NY) (241) | 62 | 59 | Mount St Mary's (270) | Final | L | -3 |
| 15 | 2022-01-15 | Bryant (317) | 52 | 68 | Mount St Mary's (294) | Final | W | 16 |
| 16 | 2022-01-17 | Merrimack (309) | 70 | 78 | Mount St Mary's (294) | Final | W | 8 |
| 17 | 2022-01-21 | Mount St Mary's (267) | 60 | 51 | Sacred Heart (255) | Final | W | 9 |
| 18 | 2022-01-23 | Mount St Mary's (270) | 71 | 60 | Central Connecticut State (363) | Final | W | 11 |
| 19 | 2022-01-27 | Fairleigh Dickinson (105) | 64 | 56 | Mount St Mary's (270) | Final | L | -8 |
| 20 | 2022-01-29 | St. Francis (PA) (308) | 70 | 58 | Mount St Mary's (249) | Final | L | -12 |
| 21 | 2022-02-03 | Mount St Mary's (275) | 68 | 58 | Merrimack (306) | Final | W | 10 |
| 22 | 2022-02-05 | Mount St Mary's (270) | 68 | 52 | Bryant (184) | Final | W | 16 |
| 23 | 2022-02-10 | Wagner (327) | 51 | 53 | Mount St Mary's (270) | Final | W | 2 |
| 24 | 2022-02-17 | Mount St Mary's (251) | 53 | 58 | St. Francis (NY) (205) | Final | L | -5 |
| 25 | 2022-02-19 | Mount St Mary's (251) | 46 | 60 | Long Island (310) | Final | L | -14 |
| 26 | 2022-02-24 | Sacred Heart (301) | 40 | 63 | Mount St Mary's (263) | Final | W | 23 |
| 27 | 2022-02-26 | Central Connecticut State (328) | 47 | 64 | Mount St Mary's (263) | Final | W | 17 |
| 28 | 2022-03-03 | Mount St Mary's (257) | 61 | 48 | St. Francis (PA) (308) | Final | W | 13 |
| 29 | 2022-03-07 | St. Francis (PA) (308) | 53 | 69 | Mount St Mary's (257) | Final | W | 16 |
| 30 | 2022-03-10 | Wagner (241) | 50 | 62 | Mount St Mary's (247) | Final | W | 12 |
| 31 | 2022-03-13 | Bryant (318) | 42 | 60 | Mount St Mary's (247) | Final | W | 18 |
| 32 | 2022-03-17 | Mount St Mary's (238) | 70 | 74 | Longwood (172) | Final | L | -4 |