NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-10 | Radford (286) | 63 | 82 | Pittsburgh (144) | Final | L | -19 |
| 2 | 2021-11-14 | Marshall (155) | 68 | 64 | Radford (286) | Final | L | -4 |
| 3 | 2021-11-19 | Lenoir Rhyne | 44 | 75 | Radford (286) | Final | W | 31 |
| 4 | 2021-11-21 | Radford (286) | 31 | 83 | West Virginia (183) | Final | L | -52 |
| 5 | 2021-11-24 | Lees-McRae | 39 | 95 | Radford (301) | Final | W | 56 |
| 6 | 2021-11-27 | Radford (301) | 51 | 50 | UNC-Wilmington (290) | Final | W | 1 |
| 7 | 2021-12-01 | Furman (107) | 61 | 73 | Radford (263) | Final | W | 12 |
| 8 | 2021-12-05 | Radford (263) | 58 | 68 | American (146) | Final | L | -10 |
| 9 | 2021-12-12 | Radford (239) | 40 | 89 | Virginia Tech (29) | Final | L | -49 |
| 10 | 2021-12-18 | Charleston (90) | 77 | 59 | Radford (174) | Final | L | -18 |
| 11 | 2021-12-19 | Radford (174) | 64 | 85 | Coastal Carolina (178) | Final | L | -21 |
| 12 | 2021-12-29 | Radford (281) | 60 | 69 | UNC-Asheville (306) | Final | L | -9 |
| 13 | 2022-01-01 | Winthrop (355) | 0 | 0 | Radford (281) | Postponed | - | - |
| 14 | 2022-01-04 | Radford (296) | 0 | 0 | High Point (288) | Postponed | - | - |
| 15 | 2022-01-08 | Gardner-Webb (303) | 77 | 74 | Radford (174) | Final | L | -3 |
| 16 | 2022-01-11 | Radford (303) | 0 | 0 | North Carolina A&T (280) | Postponed | - | - |
| 17 | 2022-01-15 | Radford (303) | 63 | 74 | Presbyterian (284) | Final | L | -11 |
| 18 | 2022-01-18 | Hampton (229) | 0 | 0 | Radford (314) | Postponed | - | - |
| 19 | 2022-01-22 | Radford (314) | 41 | 58 | Campbell (167) | Final | L | -17 |
| 20 | 2022-01-25 | Radford (312) | 56 | 52 | Charleston Southern (352) | Final | W | 4 |
| 21 | 2022-01-27 | Radford (174) | 47 | 88 | North Carolina A&T (264) | Final | L | -41 |
| 22 | 2022-01-29 | Longwood (217) | 78 | 51 | Radford (312) | Final | L | -27 |
| 23 | 2022-02-01 | South Carolina Upstate (176) | 66 | 55 | Radford (325) | Final | L | -11 |
| 24 | 2022-02-05 | North Carolina A&T (264) | 77 | 63 | Radford (174) | Final | L | -14 |
| 25 | 2022-02-07 | Radford (174) | 49 | 64 | High Point (103) | Final | L | -15 |
| 26 | 2022-02-09 | High Point (103) | 65 | 57 | Radford (174) | Final | L | -8 |
| 27 | 2022-02-12 | Radford (330) | 62 | 99 | Gardner-Webb (272) | Final | L | -37 |
| 28 | 2022-02-15 | UNC-Asheville (330) | 62 | 79 | Radford (334) | Final | W | 17 |
| 29 | 2022-02-17 | Winthrop (352) | 50 | 67 | Radford (334) | Final | W | 17 |
| 30 | 2022-02-19 | Radford (334) | 47 | 62 | Winthrop (352) | Final | L | -15 |
| 31 | 2022-02-22 | Radford (333) | 53 | 59 | Hampton (279) | Final | L | -6 |
| 32 | 2022-02-24 | Hampton (279) | 54 | 51 | Radford (333) | Final | L | -3 |
| 33 | 2022-02-26 | Presbyterian (317) | 61 | 57 | Radford (333) | Final | L | -4 |
| 34 | 2022-03-01 | Radford (335) | 49 | 55 | Hampton (276) | Final | L | -6 |