NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Agnes Scott | 25 | 117 | Coastal Carolina (322) | Final | W | 92 |
| 2 | 2021-11-13 | Coastal Carolina (322) | 81 | 57 | South Carolina State (340) | Final | W | 24 |
| 3 | 2021-11-16 | Erskine | 24 | 74 | Coastal Carolina (59) | Final | W | 50 |
| 4 | 2021-11-20 | Coastal Carolina (59) | 73 | 62 | UNC-Wilmington (264) | Final | W | 11 |
| 5 | 2021-11-26 | UNC-Greensboro (254) | 41 | 53 | Coastal Carolina (178) | Final | W | 12 |
| 6 | 2021-11-28 | East Tennessee State (278) | 41 | 55 | Coastal Carolina (86) | Final | W | 14 |
| 7 | 2021-12-04 | Wofford (220) | 46 | 58 | Coastal Carolina (178) | Final | W | 12 |
| 8 | 2021-12-07 | Wesleyan | 39 | 116 | Coastal Carolina (87) | Final | W | 77 |
| 9 | 2021-12-15 | Saint Mary's (114) | 61 | 58 | Coastal Carolina (103) | Final | L | -3 |
| 10 | 2021-12-18 | Florida A&M (338) | 72 | 76 | Coastal Carolina (178) | Final | W | 4 |
| 11 | 2021-12-19 | Radford (174) | 64 | 85 | Coastal Carolina (178) | Final | W | 21 |
| 12 | 2021-12-30 | Coastal Carolina (115) | 80 | 91 | Troy (127) | Final | L | -11 |
| 13 | 2022-01-01 | Coastal Carolina (115) | 0 | 0 | South Alabama (305) | Canceled | - | - |
| 14 | 2022-01-06 | Georgia Southern (132) | 69 | 72 | Coastal Carolina (131) | Final | W | 3 |
| 15 | 2022-01-08 | Georgia State (250) | 51 | 75 | Coastal Carolina (178) | Final | W | 24 |
| 16 | 2022-01-13 | Coastal Carolina (178) | 50 | 54 | Little Rock (228) | Final | L | -4 |
| 17 | 2022-01-15 | Coastal Carolina (113) | 60 | 81 | Arkansas State (241) | Final | L | -21 |
| 18 | 2022-01-20 | Louisiana-Monroe (344) | 0 | 0 | Coastal Carolina (153) | Canceled | - | - |
| 19 | 2022-01-22 | Louisiana (119) | 0 | 0 | Coastal Carolina (153) | Canceled | - | - |
| 20 | 2022-01-26 | Coastal Carolina (154) | 61 | 66 | Appalachian State (218) | Final | L | -5 |
| 21 | 2022-01-29 | Appalachian State (218) | 70 | 68 | Coastal Carolina (154) | Final | L | -2 |
| 22 | 2022-02-05 | Coastal Carolina (178) | 59 | 64 | Texas State (255) | Final | L | -5 |
| 23 | 2022-02-10 | Coastal Carolina (178) | 69 | 62 | Georgia State (250) | Final | W | 7 |
| 24 | 2022-02-12 | Coastal Carolina (201) | 75 | 90 | Georgia Southern (172) | Final | L | -15 |
| 25 | 2022-02-19 | Texas-Arlington (93) | 70 | 61 | Coastal Carolina (206) | Final | L | -9 |
| 26 | 2022-02-24 | South Alabama (311) | 62 | 79 | Coastal Carolina (208) | Final | W | 17 |
| 27 | 2022-02-26 | Troy (97) | 71 | 58 | Coastal Carolina (208) | Final | L | -13 |
| 28 | 2022-03-02 | Coastal Carolina (205) | 91 | 76 | Arkansas State (247) | Final | W | 15 |
| 29 | 2022-03-04 | Coastal Carolina (205) | 77 | 99 | Troy (91) | Final | L | -22 |