NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-16 | St. Francis (PA) (321) | 33 | 86 | West Virginia (183) | Final | W | 53 |
| 2 | 2021-11-19 | Kennesaw State (271) | 58 | 78 | West Virginia (183) | Final | W | 20 |
| 3 | 2021-11-21 | Radford (286) | 31 | 83 | West Virginia (183) | Final | W | 52 |
| 4 | 2021-11-25 | Purdue (84) | 57 | 65 | West Virginia (15) | Final | W | 8 |
| 5 | 2021-11-27 | BYU (29) | 58 | 57 | West Virginia (46) | Final | L | -1 |
| 6 | 2021-12-01 | West Virginia (46) | 60 | 83 | Kentucky (89) | Final | L | -23 |
| 7 | 2021-12-07 | Charlotte (129) | 54 | 65 | West Virginia (73) | Final | W | 11 |
| 8 | 2021-12-12 | West Virginia (73) | 75 | 68 | James Madison (179) | Final/OT | W | 7 |
| 9 | 2021-12-20 | South Florida (29) | 77 | 55 | West Virginia (71) | Final | L | -22 |
| 10 | 2021-12-21 | West Virginia (73) | 74 | 54 | Michigan State (128) | Final | W | 20 |
| 11 | 2021-12-29 | Maryland-Eastern Shore (320) | 0 | 0 | West Virginia (63) | Cancelled | - | - |
| 12 | 2022-01-02 | West Virginia (15) | 72 | 88 | Iowa State (37) | Final | L | -16 |
| 13 | 2022-01-05 | West Virginia (15) | 0 | 0 | Kansas (49) | Postponed | - | - |
| 14 | 2022-01-08 | Kansas State (62) | 71 | 61 | West Virginia (15) | Final | L | -10 |
| 15 | 2022-01-12 | Texas Tech (26) | 53 | 64 | West Virginia (15) | Final | W | 11 |
| 16 | 2022-01-15 | West Virginia (62) | 57 | 73 | Texas (13) | Final | L | -16 |
| 17 | 2022-01-19 | Oklahoma (10) | 88 | 76 | West Virginia (15) | Final | L | -12 |
| 18 | 2022-01-22 | West Virginia (56) | 61 | 57 | Oklahoma State (87) | Final | W | 4 |
| 19 | 2022-01-25 | TCU (111) | 54 | 66 | West Virginia (57) | Final | W | 12 |
| 20 | 2022-01-29 | Baylor (20) | 87 | 54 | West Virginia (57) | Final | L | -33 |
| 21 | 2022-02-02 | West Virginia (56) | 70 | 62 | TCU (117) | Final | W | 8 |
| 22 | 2022-02-05 | West Virginia (15) | 99 | 101 | Oklahoma (10) | Final/2OT | L | -2 |
| 23 | 2022-02-09 | Kansas (49) | 65 | 47 | West Virginia (15) | Final | L | -18 |
| 24 | 2022-02-12 | West Virginia (59) | 57 | 75 | Baylor (13) | Final | L | -18 |
| 25 | 2022-02-15 | West Virginia (65) | 63 | 74 | Kansas (23) | Final | L | -11 |
| 26 | 2022-02-20 | Texas (12) | 67 | 58 | West Virginia (65) | Final | L | -9 |
| 27 | 2022-02-23 | West Virginia (69) | 73 | 62 | Texas Tech (77) | Final | W | 11 |
| 28 | 2022-02-27 | Oklahoma State (90) | 56 | 60 | West Virginia (69) | Final | W | 4 |
| 29 | 2022-03-02 | West Virginia (65) | 74 | 62 | Kansas State (30) | Final/2OT | W | 12 |
| 30 | 2022-03-05 | Iowa State (7) | 74 | 57 | West Virginia (65) | Final | L | -17 |
| 31 | 2022-03-10 | TCU (152) | 48 | 68 | West Virginia (57) | Final | W | 20 |
| 32 | 2022-03-11 | West Virginia (57) | 60 | 66 | Iowa State (7) | Final | L | -6 |