Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Portland State (292) | 64 | 73 | Oregon State (69) | Final | L | -9 |
| 2 | 2021-11-12 | Evergreen State | 44 | 100 | Portland State (192) | Final | W | 56 |
| 3 | 2021-11-17 | George Fox | 58 | 104 | Portland State (192) | Final | W | 46 |
| 4 | 2021-11-23 | Portland (147) | 69 | 54 | Portland State (232) | Final | L | -15 |
| 5 | 2021-11-26 | Portland State (192) | 51 | 85 | Iowa (28) | Final | L | -34 |
| 6 | 2021-12-02 | Portland State (294) | 63 | 55 | Idaho State (346) | Final | W | 8 |
| 7 | 2021-12-04 | Portland State (192) | 69 | 80 | Weber State (235) | Final | L | -11 |
| 8 | 2021-12-11 | Cal Poly (238) | 61 | 58 | Portland State (192) | Final | L | -3 |
| 9 | 2021-12-18 | Portland State (192) | 66 | 69 | Cal State-Northridge (180) | Final | L | -3 |
| 10 | 2021-12-21 | Portland State (192) | 62 | 81 | Utah State (25) | Final | L | -19 |
| 11 | 2021-12-30 | Eastern Washington (242) | 63 | 58 | Portland State (192) | Final | L | -5 |
| 12 | 2022-01-01 | Idaho (209) | 0 | 0 | Portland State (192) | Postponed | - | - |
| 13 | 2022-01-06 | Portland State (192) | 0 | 0 | Southern Utah (282) | Postponed | - | - |
| 14 | 2022-01-15 | Portland State (192) | 67 | 62 | Sacramento State (313) | Final | W | 5 |
| 15 | 2022-01-17 | Portland State (310) | 76 | 86 | Southern Utah (158) | Final | L | -10 |
| 16 | 2022-01-20 | Montana (230) | 66 | 64 | Portland State (192) | Final | L | -2 |
| 17 | 2022-01-22 | Montana State (197) | 73 | 60 | Portland State (192) | Final | L | -13 |
| 18 | 2022-01-24 | Idaho (209) | 84 | 79 | Portland State (192) | Final | L | -5 |
| 19 | 2022-01-27 | Southern Utah (282) | 85 | 82 | Portland State (192) | Final/OT | L | -3 |
| 20 | 2022-01-29 | Portland State (192) | 97 | 76 | Northern Arizona (324) | Final | W | 21 |
| 21 | 2022-01-31 | Northern Colorado (206) | 76 | 79 | Portland State (327) | Final | W | 3 |
| 22 | 2022-02-03 | Portland State (192) | 106 | 99 | Northern Colorado (196) | Final | W | 7 |
| 23 | 2022-02-05 | Sacramento State (313) | 65 | 73 | Portland State (192) | Final | W | 8 |
| 24 | 2022-02-10 | Portland State (192) | 74 | 77 | Montana State (197) | Final | L | -3 |
| 25 | 2022-02-12 | Portland State (192) | 76 | 85 | Montana (230) | Final | L | -9 |
| 26 | 2022-02-17 | Northern Arizona (324) | 67 | 68 | Portland State (192) | Final | W | 1 |
| 27 | 2022-02-24 | Weber State (155) | 75 | 81 | Portland State (293) | Final | W | 6 |
| 28 | 2022-02-26 | Idaho State (339) | 69 | 73 | Portland State (293) | Final | W | 4 |
| 29 | 2022-03-03 | Portland State (282) | 79 | 68 | Idaho (320) | Final | W | 11 |
| 30 | 2022-03-05 | Portland State (282) | 75 | 83 | Eastern Washington (228) | Final | L | -8 |
| 31 | 2022-03-09 | Idaho State (341) | 52 | 66 | Portland State (276) | Final | W | 14 |
| 32 | 2022-03-10 | Portland State (276) | 77 | 65 | Southern Utah (158) | Final | W | 12 |
| 33 | 2022-03-11 | Portland State (276) | 79 | 86 | Northern Colorado (215) | Final | L | -7 |