NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-10 | Colorado (99) | 55 | 45 | Oklahoma State (26) | Final | L | -10 |
| 2 | 2021-11-14 | Oklahoma State (26) | 67 | 50 | SMU (284) | Final | W | 17 |
| 3 | 2021-11-17 | Missouri State (33) | 40 | 44 | Oklahoma State (123) | Final | W | 4 |
| 4 | 2021-11-20 | Oklahoma State (123) | 68 | 48 | Rice (236) | Final | W | 20 |
| 5 | 2021-11-26 | Green Bay (89) | 57 | 54 | Oklahoma State (32) | Final | L | -3 |
| 6 | 2021-11-27 | Oklahoma State (40) | 55 | 80 | Tennessee (8) | Final | L | -25 |
| 7 | 2021-12-05 | Oklahoma State (94) | 66 | 77 | Auburn (154) | Final | L | -11 |
| 8 | 2021-12-15 | Southern (302) | 33 | 75 | Oklahoma State (99) | Final | W | 42 |
| 9 | 2021-12-17 | Texas-Arlington (50) | 46 | 61 | Oklahoma State (99) | Final | W | 15 |
| 10 | 2021-12-21 | North Texas (104) | 0 | 0 | Oklahoma State (79) | Cancelled | - | - |
| 11 | 2021-12-28 | Tulsa (140) | 0 | 0 | Oklahoma State (32) | Cancelled | - | - |
| 12 | 2022-01-02 | Texas (4) | 62 | 51 | Oklahoma State (32) | Final | L | -11 |
| 13 | 2022-01-05 | Kansas State (62) | 60 | 49 | Oklahoma State (32) | Final | L | -11 |
| 14 | 2022-01-08 | Oklahoma State (32) | 57 | 55 | Texas Tech (26) | Final | W | 2 |
| 15 | 2022-01-12 | Oklahoma State (32) | 63 | 64 | TCU (12) | Final | L | -1 |
| 16 | 2022-01-15 | Iowa State (6) | 74 | 60 | Oklahoma State (65) | Final | L | -14 |
| 17 | 2022-01-19 | Oklahoma State (32) | 49 | 67 | Baylor (24) | Final | L | -18 |
| 18 | 2022-01-22 | West Virginia (56) | 61 | 57 | Oklahoma State (87) | Final | L | -4 |
| 19 | 2022-01-26 | Oklahoma State (94) | 58 | 84 | Oklahoma (11) | Final | L | -26 |
| 20 | 2022-01-29 | Kansas (30) | 68 | 54 | Oklahoma State (94) | Final | L | -14 |
| 21 | 2022-02-02 | Oklahoma State (98) | 56 | 65 | Kansas (33) | Final | L | -9 |
| 22 | 2022-02-05 | Oklahoma State (32) | 58 | 76 | Iowa State (37) | Final | L | -18 |
| 23 | 2022-02-09 | TCU (12) | 47 | 76 | Oklahoma State (32) | Final | W | 29 |
| 24 | 2022-02-12 | Texas Tech (77) | 58 | 62 | Oklahoma State (104) | Final | W | 4 |
| 25 | 2022-02-19 | Oklahoma State | Kansas State | TBD | - | - | ||
| 26 | 2022-02-20 | Oklahoma State (88) | 38 | 56 | Kansas State (27) | Final | L | -18 |
| 27 | 2022-02-23 | Baylor (7) | 65 | 58 | Oklahoma State (90) | Final | L | -7 |
| 28 | 2022-02-27 | Oklahoma State (90) | 56 | 60 | West Virginia (69) | Final | L | -4 |
| 29 | 2022-03-02 | Oklahoma (13) | 79 | 76 | Oklahoma State (93) | Final | L | -3 |
| 30 | 2022-03-05 | Oklahoma State (93) | 50 | 65 | Texas (9) | Final | L | -15 |
| 31 | 2022-03-10 | Oklahoma State (94) | 73 | 58 | Texas Tech (80) | Final | W | 15 |
| 32 | 2022-03-11 | Oklahoma State (94) | 36 | 76 | Baylor (5) | Final | L | -40 |