NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Lipscomb (219) | 58 | 81 | BYU (47) | Final | L | -23 |
| 2 | 2021-11-10 | Lipscomb (219) | 56 | 105 | Utah (162) | Final | L | -49 |
| 3 | 2021-11-16 | Shorter | 50 | 73 | Lipscomb (301) | Final | W | 23 |
| 4 | 2021-11-21 | Lipscomb (301) | 55 | 81 | Colorado State (88) | Final | L | -26 |
| 5 | 2021-11-28 | Life | 59 | 72 | Lipscomb (293) | Final | W | 13 |
| 6 | 2021-12-02 | Lipscomb (288) | 62 | 67 | Belmont (120) | Final | L | -5 |
| 7 | 2021-12-05 | Middle Tennessee (44) | 84 | 59 | Lipscomb (288) | Final | L | -25 |
| 8 | 2021-12-08 | LaGrange | 45 | 77 | Lipscomb (294) | Final | W | 32 |
| 9 | 2021-12-12 | Tennessee Wesleyan | 44 | 86 | Lipscomb (294) | Final | W | 42 |
| 10 | 2021-12-15 | Tennessee State (264) | 50 | 49 | Lipscomb (299) | Final | L | -1 |
| 11 | 2021-12-18 | Lipscomb (286) | 50 | 74 | Murray State (52) | Final | L | -24 |
| 12 | 2021-12-20 | Lipscomb (299) | 54 | 47 | Eastern Illinois (195) | Final | W | 7 |
| 13 | 2021-12-29 | Lipscomb (287) | 0 | 0 | Cincinnati (167) | Cancelled | - | - |
| 14 | 2021-12-30 | Lipscomb (287) | 54 | 70 | Arizona State (67) | Final | L | -16 |
| 15 | 2022-01-05 | North Alabama (230) | 0 | 0 | Lipscomb (286) | Postponed | - | - |
| 16 | 2022-01-08 | Lipscomb (286) | 0 | 0 | Central Arkansas (131) | Postponed | - | - |
| 17 | 2022-01-12 | Lipscomb (286) | 70 | 80 | Jacksonville State (231) | Final | L | -10 |
| 18 | 2022-01-15 | Bellarmine (329) | 54 | 65 | Lipscomb (274) | Final | W | 11 |
| 19 | 2022-01-17 | Lipscomb (274) | 63 | 54 | Central Arkansas (291) | Final | W | 9 |
| 20 | 2022-01-19 | Lipscomb (286) | 41 | 77 | Eastern Kentucky (111) | Final | L | -36 |
| 21 | 2022-01-22 | Kennesaw State (251) | 53 | 61 | Lipscomb (264) | Final | W | 8 |
| 22 | 2022-01-27 | Lipscomb (286) | 51 | 58 | Jacksonville (118) | Final | L | -7 |
| 23 | 2022-01-29 | Lipscomb (268) | 75 | 83 | North Florida (211) | Final/OT | L | -8 |
| 24 | 2022-02-03 | Stetson (169) | 61 | 50 | Lipscomb (279) | Final | L | -11 |
| 25 | 2022-02-05 | Florida Gulf Coast (172) | 73 | 55 | Lipscomb (286) | Final | L | -18 |
| 26 | 2022-02-09 | Lipscomb (286) | 51 | 64 | Liberty (144) | Final | L | -13 |
| 27 | 2022-02-12 | Eastern Kentucky (274) | 82 | 69 | Lipscomb (285) | Final | L | -13 |
| 28 | 2022-02-14 | North Alabama (286) | 76 | 68 | Lipscomb (285) | Final | L | -8 |
| 29 | 2022-02-17 | Jacksonville State (130) | 62 | 53 | Lipscomb (294) | Final | L | -9 |
| 30 | 2022-02-19 | Lipscomb (294) | 70 | 59 | North Alabama (273) | Final | W | 11 |
| 31 | 2022-02-24 | Lipscomb (292) | 48 | 68 | Bellarmine (343) | Final | L | -20 |
| 32 | 2022-02-26 | Central Arkansas (302) | 46 | 50 | Lipscomb (292) | Final | W | 4 |
| 33 | 2022-03-02 | North Florida (242) | 60 | 42 | Lipscomb (298) | Final | L | -18 |