NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Stephens | 33 | 88 | Indiana State (282) | Final | W | 55 |
| 2 | 2021-11-14 | Indiana State (282) | 58 | 65 | Saint Louis (79) | Final | L | -7 |
| 3 | 2021-11-17 | Eastern Illinois (143) | 64 | 55 | Indiana State (246) | Final | L | -9 |
| 4 | 2021-11-24 | Indiana State (264) | 65 | 83 | Western Kentucky (263) | Final | L | -18 |
| 5 | 2021-11-26 | Jacksonville State (231) | 67 | 57 | Indiana State (285) | Final | L | -10 |
| 6 | 2021-11-27 | Indiana State (264) | 71 | 67 | Georgia Southern (262) | Final | W | 4 |
| 7 | 2021-12-01 | Indiana State (281) | 59 | 58 | Chicago State (324) | Final | W | 1 |
| 8 | 2021-12-04 | Western Michigan (281) | 68 | 67 | Indiana State (285) | Final | L | -1 |
| 9 | 2021-12-11 | Indiana State (267) | 50 | 78 | Nebraska (5) | Final | L | -28 |
| 10 | 2021-12-14 | Illinois-Chicago (307) | 50 | 76 | Indiana State (263) | Final | W | 26 |
| 11 | 2021-12-20 | Indiana State (243) | 55 | 53 | Purdue Fort Wayne (306) | Final | W | 2 |
| 12 | 2021-12-30 | Indiana State (235) | 78 | 70 | Drake (48) | Final | W | 8 |
| 13 | 2022-01-01 | Indiana State (235) | 0 | 0 | Northern Iowa (81) | Postponed | - | - |
| 14 | 2022-01-07 | Illinois State (258) | 66 | 58 | Indiana State (195) | Final | L | -8 |
| 15 | 2022-01-09 | Bradley (155) | 57 | 73 | Indiana State (285) | Final | W | 16 |
| 16 | 2022-01-13 | Evansville (272) | 0 | 0 | Indiana State (285) | Postponed | - | - |
| 17 | 2022-01-18 | Evansville (266) | 51 | 69 | Indiana State (215) | Final | W | 18 |
| 18 | 2022-01-21 | Indiana State (215) | 85 | 65 | Valparaiso (273) | Final | W | 20 |
| 19 | 2022-01-23 | Indiana State (285) | 0 | 0 | Loyola-Chicago (175) | Postponed | - | - |
| 20 | 2022-01-27 | Southern Illinois (291) | 0 | 0 | Indiana State (285) | Postponed | - | - |
| 21 | 2022-01-29 | Missouri State (45) | 62 | 58 | Indiana State (189) | Final | L | -4 |
| 22 | 2022-02-02 | Indiana State (192) | 49 | 72 | Northern Iowa (73) | Final | L | -23 |
| 23 | 2022-02-04 | Indiana State (192) | 83 | 63 | Bradley (309) | Final | W | 20 |
| 24 | 2022-02-06 | Indiana State (192) | 64 | 72 | Illinois State (161) | Final | L | -8 |
| 25 | 2022-02-09 | Southern Illinois (291) | 79 | 55 | Indiana State (285) | Final | L | -24 |
| 26 | 2022-02-12 | Indiana State (198) | 56 | 58 | Evansville (299) | Final | L | -2 |
| 27 | 2022-02-15 | Indiana State (223) | 40 | 64 | Loyola-Chicago (166) | Final | L | -24 |
| 28 | 2022-02-18 | Loyola-Chicago (166) | 61 | 59 | Indiana State (223) | Final | L | -2 |
| 29 | 2022-02-20 | Valparaiso (268) | 74 | 69 | Indiana State (223) | Final | L | -5 |
| 30 | 2022-02-24 | Indiana State (246) | 46 | 63 | Southern Illinois (83) | Final | L | -17 |
| 31 | 2022-02-26 | Indiana State (246) | 65 | 72 | Missouri State (42) | Final | L | -7 |
| 32 | 2022-03-03 | Northern Iowa (74) | 61 | 55 | Indiana State (241) | Final | L | -6 |
| 33 | 2022-03-05 | Drake (100) | 86 | 71 | Indiana State (241) | Final | L | -15 |
| 34 | 2022-03-10 | Evansville (301) | 75 | 89 | Indiana State (245) | Final | W | 14 |
| 35 | 2022-03-11 | Indiana State (245) | 61 | 77 | Southern Illinois (89) | Final | L | -16 |