NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-10 | Illinois-Chicago (315) | 49 | 72 | Northwestern (38) | Final | L | -23 |
| 2 | 2021-11-18 | Illinois-Chicago (201) | 63 | 69 | Purdue Fort Wayne (148) | Final | L | -6 |
| 3 | 2021-11-20 | Illinois-Chicago (242) | 64 | 74 | Cleveland State (40) | Final | L | -10 |
| 4 | 2021-11-23 | Valparaiso (360) | 64 | 68 | Illinois-Chicago (201) | Final | W | 4 |
| 5 | 2021-11-29 | Nebraska-Omaha (315) | 70 | 58 | Illinois-Chicago (277) | Final | L | -12 |
| 6 | 2021-12-02 | Illinois-Chicago (309) | 59 | 67 | Oakland (200) | Final | L | -8 |
| 7 | 2021-12-04 | Illinois-Chicago (201) | 68 | 64 | Detroit (320) | Final/OT | W | 4 |
| 8 | 2021-12-14 | Illinois-Chicago (307) | 50 | 76 | Indiana State (263) | Final | L | -26 |
| 9 | 2021-12-18 | Saint Louis (206) | 75 | 47 | Illinois-Chicago (201) | Final | L | -28 |
| 10 | 2021-12-22 | Illinois-Chicago (325) | 0 | 0 | Kansas State (20) | Cancelled | - | - |
| 11 | 2021-12-31 | Wright State | Illinois-Chicago | Cancelled | - | - | ||
| 12 | 2022-01-02 | Northern Kentucky (193) | 0 | 0 | Illinois-Chicago (201) | Canceled | - | - |
| 13 | 2022-01-06 | Milwaukee (243) | 65 | 58 | Illinois-Chicago (332) | Final | L | -7 |
| 14 | 2022-01-08 | Green Bay (89) | 75 | 38 | Illinois-Chicago (201) | Final | L | -37 |
| 15 | 2022-01-14 | Illinois-Chicago (332) | 46 | 69 | Youngstown State (93) | Final | L | -23 |
| 16 | 2022-01-16 | Illinois-Chicago (201) | 44 | 50 | Robert Morris (215) | Final | L | -6 |
| 17 | 2022-01-21 | Illinois-Chicago (335) | 44 | 82 | IUPUI (73) | Final | L | -38 |
| 18 | 2022-01-23 | IU-Indy (247) | 68 | 47 | Illinois-Chicago (201) | Final | L | -21 |
| 19 | 2022-01-27 | Cleveland State (133) | 54 | 45 | Illinois-Chicago (201) | Final | L | -9 |
| 20 | 2022-01-29 | Purdue Fort Wayne (333) | 88 | 61 | Illinois-Chicago (337) | Final | L | -27 |
| 21 | 2022-02-01 | Northern Kentucky (122) | 71 | 41 | Illinois-Chicago (339) | Final | L | -30 |
| 22 | 2022-02-04 | Detroit (355) | 0 | 0 | Illinois-Chicago (339) | Postponed | - | - |
| 23 | 2022-02-06 | Oakland (203) | 59 | 47 | Illinois-Chicago (339) | Final | L | -12 |
| 24 | 2022-02-10 | Illinois-Chicago (201) | 57 | 67 | Northern Kentucky (193) | Final | L | -10 |
| 25 | 2022-02-12 | Illinois-Chicago (340) | 63 | 69 | Wright State (336) | Final | L | -6 |
| 26 | 2022-02-14 | Detroit (355) | 63 | 61 | Illinois-Chicago (340) | Final | L | -2 |
| 27 | 2022-02-17 | Illinois-Chicago (346) | 46 | 75 | Green Bay (106) | Final | L | -29 |
| 28 | 2022-02-19 | Illinois-Chicago (346) | 57 | 65 | Milwaukee (215) | Final | L | -8 |
| 29 | 2022-02-24 | Robert Morris (251) | 57 | 50 | Illinois-Chicago (346) | Final | L | -7 |
| 30 | 2022-02-26 | Youngstown State (98) | 61 | 54 | Illinois-Chicago (346) | Final | L | -7 |
| 31 | 2022-03-01 | Illinois-Chicago (348) | 46 | 55 | Milwaukee (203) | Final | L | -9 |