NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Detroit (327) | 40 | 63 | Loyola-Chicago (160) | Final | W | 23 |
| 2 | 2021-11-12 | Loyola-Chicago (175) | 53 | 87 | DePaul (229) | Final | L | -34 |
| 3 | 2021-11-17 | Loyola-Chicago (206) | 47 | 63 | Northwestern (41) | Final | L | -16 |
| 4 | 2021-11-20 | Chicago State (347) | 59 | 71 | Loyola-Chicago (206) | Final | W | 12 |
| 5 | 2021-11-24 | St. Francis (IL) | 61 | 96 | Loyola-Chicago (191) | Final | W | 35 |
| 6 | 2021-11-28 | Miami (OH) (157) | 52 | 69 | Loyola-Chicago (191) | Final | W | 17 |
| 7 | 2021-12-03 | Loyola-Chicago (169) | 73 | 37 | Dartmouth (345) | Final | W | 36 |
| 8 | 2021-12-05 | Loyola-Chicago (169) | 62 | 72 | Vermont (278) | Final | L | -10 |
| 9 | 2021-12-08 | Eastern Illinois (190) | 48 | 58 | Loyola-Chicago (194) | Final | W | 10 |
| 10 | 2021-12-11 | Loyola-Chicago (194) | 69 | 48 | Central Michigan (250) | Final | W | 21 |
| 11 | 2021-12-21 | Loyola-Chicago (155) | 66 | 52 | Cleveland State (78) | Final | W | 14 |
| 12 | 2021-12-31 | Loyola-Chicago (175) | 38 | 55 | Missouri State (110) | Final | L | -17 |
| 13 | 2022-01-02 | Loyola-Chicago (175) | 50 | 63 | Southern Illinois (291) | Final | L | -13 |
| 14 | 2022-01-07 | Drake (58) | 46 | 63 | Loyola-Chicago (155) | Final | W | 17 |
| 15 | 2022-01-09 | Northern Iowa (132) | 58 | 54 | Loyola-Chicago (175) | Final | L | -4 |
| 16 | 2022-01-13 | Loyola-Chicago (175) | 48 | 41 | Bradley (155) | Final | W | 7 |
| 17 | 2022-01-15 | Loyola-Chicago (138) | 50 | 68 | Illinois State (226) | Final | L | -18 |
| 18 | 2022-01-21 | Evansville (266) | 54 | 68 | Loyola-Chicago (161) | Final | W | 14 |
| 19 | 2022-01-23 | Indiana State (285) | 0 | 0 | Loyola-Chicago (175) | Postponed | - | - |
| 20 | 2022-01-28 | Valparaiso (273) | 48 | 62 | Loyola-Chicago (161) | Final | W | 14 |
| 21 | 2022-02-04 | Loyola-Chicago (150) | 56 | 69 | Northern Iowa (73) | Final | L | -13 |
| 22 | 2022-02-06 | Loyola-Chicago (150) | 76 | 84 | Drake (110) | Final | L | -8 |
| 23 | 2022-02-10 | Illinois State (136) | 57 | 53 | Loyola-Chicago (175) | Final | L | -4 |
| 24 | 2022-02-12 | Bradley (300) | 41 | 56 | Loyola-Chicago (158) | Final | W | 15 |
| 25 | 2022-02-15 | Indiana State (223) | 40 | 64 | Loyola-Chicago (166) | Final | W | 24 |
| 26 | 2022-02-18 | Loyola-Chicago (166) | 61 | 59 | Indiana State (223) | Final | W | 2 |
| 27 | 2022-02-20 | Loyola-Chicago (166) | 60 | 56 | Evansville (291) | Final | W | 4 |
| 28 | 2022-02-25 | Loyola-Chicago (175) | 66 | 52 | Valparaiso (360) | Final | W | 14 |
| 29 | 2022-03-03 | Southern Illinois (82) | 51 | 28 | Loyola-Chicago (149) | Final | L | -23 |
| 30 | 2022-03-05 | Missouri State (41) | 42 | 60 | Loyola-Chicago (149) | Final | W | 18 |
| 31 | 2022-03-11 | Loyola-Chicago (141) | 52 | 68 | Illinois State (167) | Final | L | -16 |