Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-01 | Duquesne | 10 | Youngstown State | 45 | Final | W | 35 |
| 2 | 2016-09-10 | Youngstown State | 21 | West Virginia | 38 | Final | L | -17 |
| 3 | 2016-09-17 | Robert Morris | 6 | Youngstown State | 38 | Final | W | 32 |
| 4 | 2016-10-01 | South Dakota | 20 | Youngstown State | 30 | Final | W | 10 |
| 5 | 2016-10-08 | Youngstown State | 20 | Illinois State | 6 | Final | W | 14 |
| 6 | 2016-10-15 | Northern Iowa | 10 | Youngstown State | 14 | Final | W | 4 |
| 7 | 2016-10-22 | Youngstown State | 10 | South Dakota State | 24 | Final | L | -14 |
| 8 | 2016-10-29 | Indiana State | 10 | Youngstown State | 13 | Final | W | 3 |
| 9 | 2016-11-05 | Youngstown State | 3 | North Dakota State | 24 | Final | L | -21 |
| 10 | 2016-11-12 | Southern Illinois | 14 | Youngstown State | 21 | Final | W | 7 |
| 11 | 2016-11-19 | Youngstown State | 65 | Missouri State | 20 | Final | W | 45 |
| 12 | 2016-11-26 | Samford | 24 | Youngstown State | 38 | Final | W | 14 |
| 13 | 2016-12-03 | Youngstown State | 40 | Jacksonville State | 24 | Final | W | 16 |
| 14 | 2016-12-10 | Wofford | 23 | Youngstown State | 30 | Final/2OT | W | 7 |
| 15 | 2016-12-17 | Youngstown State | 40 | Eastern Washington | 38 | Final | W | 2 |
| 16 | 2017-01-07 | Youngstown State | 14 | James Madison | 28 | Final | L | -14 |