Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-03 | Northern Iowa | 25 | Iowa State | 20 | Final | W | 5 |
| 2 | 2016-09-10 | Montana | 20 | Northern Iowa | 14 | Final | L | -6 |
| 3 | 2016-09-17 | Northern Iowa | 30 | Eastern Washington | 34 | Final | L | -4 |
| 4 | 2016-10-01 | Southern Illinois | 21 | Northern Iowa | 42 | Final | W | 21 |
| 5 | 2016-10-08 | Northern Iowa | 25 | South Dakota | 28 | Final | L | -3 |
| 6 | 2016-10-15 | Northern Iowa | 10 | Youngstown State | 14 | Final | L | -4 |
| 7 | 2016-10-22 | Missouri State | 7 | Northern Iowa | 61 | Final | W | 54 |
| 8 | 2016-10-29 | North Dakota State | 24 | Northern Iowa | 20 | Final | L | -4 |
| 9 | 2016-11-05 | Northern Iowa (153) | 39 | Indiana State (181) | 6 | Final | W | 33 |
| 10 | 2016-11-12 | Northern Iowa | 30 | Western Illinois | 23 | Final | W | 7 |
| 11 | 2016-11-19 | South Dakota State | 45 | Northern Iowa | 24 | Final | L | -21 |