Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-01 | Duquesne | 10 | Youngstown State | 45 | Final | L | -35 |
| 2 | 2016-09-10 | Bucknell | 19 | Duquesne | 30 | Final | W | 11 |
| 3 | 2016-09-17 | Dayton | 20 | Duquesne | 34 | Final | W | 14 |
| 4 | 2016-09-24 | Kennesaw State | 36 | Duquesne | 28 | Final | L | -8 |
| 5 | 2016-10-01 | Duquesne | 54 | Jacksonville | 35 | Final | W | 19 |
| 6 | 2016-10-15 | Robert Morris | 24 | Duquesne | 31 | Final | W | 7 |
| 7 | 2016-10-29 | Bryant (224) | 31 | Duquesne (184) | 35 | Final | W | 4 |
| 8 | 2016-11-05 | Duquesne (179) | 28 | Wagner (202) | 20 | Final | W | 8 |
| 9 | 2016-11-12 | Sacred Heart (189) | 10 | Duquesne (175) | 31 | Final | W | 21 |
| 10 | 2016-11-19 | Duquesne | 52 | Central Connecticut State | 19 | Final | W | 33 |