Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-02 | Tennessee Tech (239) | 10 | Kansas (130) | 56 | Final | W | 46 |
| 2 | 2022-09-10 | Kansas (130) | 55 | West Virginia (52) | 42 | Final(OT) | W | 13 |
| 3 | 2022-09-17 | Kansas (20) | 48 | Houston (82) | 30 | Final | W | 18 |
| 4 | 2022-09-24 | Duke (45) | 27 | Kansas (7) | 35 | Final | W | 8 |
| 5 | 2022-10-01 | Iowa State (48) | 11 | Kansas (6) | 14 | Final | W | 3 |
| 6 | 2022-10-08 | TCU (9) | 38 | Kansas (18) | 31 | Final | L | -7 |
| 7 | 2022-10-15 | Kansas (26) | 42 | Oklahoma (35) | 52 | Final | L | -10 |
| 8 | 2022-10-22 | Kansas (34) | 23 | Baylor (44) | 35 | Final | L | -12 |
| 9 | 2022-11-05 | Oklahoma State (25) | 16 | Kansas (23) | 37 | Final | W | 21 |
| 10 | 2022-11-12 | Kansas (32) | 28 | Texas Tech (36) | 43 | Final | L | -15 |
| 11 | 2022-11-19 | Texas (12) | 55 | Kansas (43) | 14 | Final | L | -41 |
| 12 | 2022-11-26 | Kansas (48) | 27 | Kansas State (9) | 47 | Final | L | -20 |
| 13 | 2022-12-28 | Kansas (47) | 53 | Arkansas (48) | 55 | Final(3OT) | L | -2 |