Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-03 | South Dakota (140) | 0 | Kansas State (37) | 34 | Final | W | 34 |
| 2 | 2022-09-10 | Missouri (72) | 12 | Kansas State (37) | 40 | Final | W | 28 |
| 3 | 2022-09-17 | Tulane (13) | 17 | Kansas State (43) | 10 | Final | L | -7 |
| 4 | 2022-09-24 | Kansas State (32) | 41 | Oklahoma (33) | 34 | Final | W | 7 |
| 5 | 2022-10-01 | Texas Tech (41) | 28 | Kansas State (22) | 37 | Final | W | 9 |
| 6 | 2022-10-08 | Kansas State (21) | 10 | Iowa State (56) | 9 | Final | W | 1 |
| 7 | 2022-10-22 | Kansas State (21) | 28 | TCU (5) | 38 | Final | L | -10 |
| 8 | 2022-10-29 | Oklahoma State (17) | 0 | Kansas State (12) | 48 | Final | W | 48 |
| 9 | 2022-11-05 | Texas (15) | 34 | Kansas State (17) | 27 | Final | L | -7 |
| 10 | 2022-11-12 | Kansas State (14) | 31 | Baylor (38) | 3 | Final | W | 28 |
| 11 | 2022-11-19 | Kansas State (13) | 48 | West Virginia (71) | 31 | Final | W | 17 |
| 12 | 2022-11-26 | Kansas (48) | 27 | Kansas State (9) | 47 | Final | W | 20 |
| 13 | 2022-12-03 | Kansas State (8) | 31 | TCU (4) | 28 | Final(OT) | W | 3 |
| 14 | 2022-12-31 | Alabama (6) | 45 | Kansas State (8) | 20 | Final | L | -25 |