Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-01 | West Virginia (52) | 31 | Pittsburgh (11) | 38 | Final | L | -7 |
| 2 | 2022-09-10 | Kansas (130) | 55 | West Virginia (52) | 42 | Final(OT) | L | -13 |
| 3 | 2022-09-17 | Towson (171) | 7 | West Virginia (85) | 65 | Final | W | 58 |
| 4 | 2022-09-22 | West Virginia (65) | 33 | Virginia Tech (99) | 10 | Final | W | 23 |
| 5 | 2022-10-01 | West Virginia (79) | 20 | Texas (27) | 38 | Final | L | -18 |
| 6 | 2022-10-13 | Baylor (55) | 40 | West Virginia (56) | 43 | Final | W | 3 |
| 7 | 2022-10-22 | West Virginia (76) | 10 | Texas Tech (27) | 48 | Final | L | -38 |
| 8 | 2022-10-29 | TCU (4) | 41 | West Virginia (78) | 31 | Final | L | -10 |
| 9 | 2022-11-05 | West Virginia (79) | 14 | Iowa State (53) | 31 | Final | L | -17 |
| 10 | 2022-11-12 | Oklahoma (47) | 20 | West Virginia (71) | 23 | Final | W | 3 |
| 11 | 2022-11-19 | Kansas State (13) | 48 | West Virginia (71) | 31 | Final | L | -17 |
| 12 | 2022-11-26 | West Virginia (67) | 24 | Oklahoma State (44) | 19 | Final | W | 5 |