Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-03 | Southern Illinois (137) | 29 | Incarnate Word (134) | 64 | Final | W | 35 |
| 2 | 2022-09-10 | Incarnate Word (134) | 55 | Nevada (49) | 41 | Final | W | 14 |
| 3 | 2022-09-17 | Incarnate Word (91) | 31 | Prairie View A&M (181) | 14 | Final | W | 17 |
| 4 | 2022-09-24 | Incarnate Word (121) | 35 | Southeastern Louisiana (144) | 41 | Final | L | -6 |
| 5 | 2022-10-01 | McNeese State (237) | 20 | Incarnate Word (116) | 48 | Final | W | 28 |
| 6 | 2022-10-08 | Lamar (259) | 17 | Incarnate Word (124) | 56 | Final | W | 39 |
| 7 | 2022-10-15 | Incarnate Word (122) | 49 | Nicholls State (244) | 14 | Final | W | 35 |
| 8 | 2022-10-22 | Faulkner | 0 | Incarnate Word (117) | 70 | Final | W | 70 |
| 9 | 2022-10-29 | Incarnate Word (115) | 35 | Texas A&M-Commerce (187) | 7 | Final | W | 28 |
| 10 | 2022-11-05 | Houston Christian | 20 | Incarnate Word (116) | 73 | Final | W | 53 |
| 11 | 2022-11-19 | Incarnate Word (122) | 66 | Northwestern State (233) | 7 | Final | W | 59 |
| 12 | 2022-12-02 | Furman (127) | 38 | Incarnate Word (112) | 41 | Final | W | 3 |
| 13 | 2022-12-03 | Furman (130) | 38 | Incarnate Word (94) | 41 | Final | W | 3 |
| 14 | 2022-12-09 | Incarnate Word (94) | 66 | Sacramento State (61) | 63 | Final | W | 3 |
| 15 | 2022-12-16 | Incarnate Word (94) | 32 | North Dakota State (114) | 35 | Final | L | -3 |