Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-01 | Alabama A&M (168) | 0 | UAB (46) | 59 | Final | L | -59 |
| 2 | 2022-09-10 | Alabama A&M (168) | 17 | Troy (100) | 38 | Final | L | -21 |
| 3 | 2022-09-17 | Austin Peay (144) | 28 | Alabama A&M (225) | 3 | Final | L | -25 |
| 4 | 2022-09-24 | Alabama A&M (242) | 25 | Florida A&M (204) | 38 | Final | L | -13 |
| 5 | 2022-10-01 | Bethune-Cookman (236) | 27 | Alabama A&M (224) | 35 | Final | W | 8 |
| 6 | 2022-10-08 | Grambling (248) | 31 | Alabama A&M (217) | 37 | Final(OT) | W | 6 |
| 7 | 2022-10-16 | Alabama A&M (214) | 34 | Arkansas-Pine Bluff (238) | 31 | Final | W | 3 |
| 8 | 2022-10-29 | Alabama State (191) | 24 | Alabama A&M (214) | 17 | Final | L | -7 |
| 9 | 2022-11-03 | Alabama A&M (229) | 20 | Mississippi Valley State (259) | 30 | Final | L | -10 |
| 10 | 2022-11-12 | Jackson State (109) | 27 | Alabama A&M (230) | 13 | Final | L | -14 |
| 11 | 2022-11-19 | Texas Southern (195) | 20 | Alabama A&M (215) | 24 | Final | W | 4 |