Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Tennessee Tech (310) | 59 | 89 | Indiana (46) | Final | W | 30 |
| 2 | 2020-11-30 | Indiana (46) | 79 | 58 | Providence (82) | Final | W | 21 |
| 3 | 2020-12-01 | Texas (41) | 66 | 44 | Indiana (46) | Final | L | -22 |
| 4 | 2020-12-02 | Indiana (46) | 79 | 63 | Stanford (60) | Final | W | 16 |
| 5 | 2020-12-09 | Indiana (46) | 67 | 69 | Florida State (64) | Final/OT | L | -2 |
| 6 | 2020-12-13 | North Alabama (335) | 52 | 87 | Indiana (46) | Final | W | 35 |
| 7 | 2020-12-19 | Butler (80) | 60 | 68 | Indiana (46) | Final | W | 8 |
| 8 | 2020-12-19 | Indiana (43) | 68 | 60 | Butler (152) | Final | W | 8 |
| 9 | 2020-12-23 | Northwestern (75) | 74 | 67 | Indiana (46) | Final | L | -7 |
| 10 | 2020-12-26 | Indiana (46) | 60 | 69 | Illinois (9) | Final | L | -9 |
| 11 | 2020-12-30 | Penn State (129) | 85 | 87 | Indiana (46) | Final/OT | W | 2 |
| 12 | 2021-01-04 | Maryland (114) | 55 | 63 | Indiana (46) | Final | W | 8 |
| 13 | 2021-01-07 | Indiana (46) | 73 | 80 | Wisconsin (24) | Final/2OT | L | -7 |
| 14 | 2021-01-10 | Indiana (46) | 84 | 76 | Nebraska (13) | Final | W | 8 |
| 15 | 2021-01-14 | Purdue (8) | 81 | 69 | Indiana (46) | Final | L | -12 |
| 16 | 2021-01-17 | Indiana (46) | 0 | 0 | Michigan State (10) | Postponed | - | - |
| 17 | 2021-01-21 | Indiana (46) | 81 | 69 | Iowa (28) | Final | W | 12 |
| 18 | 2021-01-24 | Rutgers (112) | 74 | 70 | Indiana (46) | Final | L | -4 |
| 19 | 2021-01-30 | Indiana (46) | 0 | 0 | Michigan (1) | Cancelled | - | - |
| 20 | 2021-02-02 | Illinois (9) | 75 | 71 | Indiana (46) | Final/OT | L | -4 |
| 21 | 2021-02-07 | Iowa (28) | 65 | 67 | Indiana (46) | Final | W | 2 |
| 22 | 2021-02-10 | Indiana (46) | 79 | 76 | Northwestern (75) | Final/2OT | W | 3 |
| 23 | 2021-02-13 | Indiana (46) | 59 | 78 | Ohio State (34) | Final | L | -19 |
| 24 | 2021-02-17 | Minnesota (87) | 72 | 82 | Indiana (46) | Final | W | 10 |
| 25 | 2021-02-20 | Michigan State (10) | 78 | 71 | Indiana (46) | Final | L | -7 |
| 26 | 2021-02-24 | Indiana (46) | 63 | 74 | Rutgers (112) | Final | L | -11 |
| 27 | 2021-02-27 | Michigan (1) | 73 | 57 | Indiana (46) | Final | L | -16 |
| 28 | 2021-03-02 | Indiana (46) | 58 | 64 | Michigan State (10) | Final | L | -6 |
| 29 | 2021-03-06 | Indiana (46) | 58 | 67 | Purdue (8) | Final | L | -9 |
| 30 | 2021-03-11 | Indiana (46) | 50 | 61 | Rutgers (112) | Final | L | -11 |