NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-11 | Southeastern Louisiana (349) | 45 | 67 | Texas Tech (26) | Final | W | 22 |
| 2 | 2021-11-16 | Weber State (161) | 44 | 62 | Texas Tech (99) | Final | W | 18 |
| 3 | 2021-11-19 | Lamar (212) | 68 | 72 | Texas Tech (99) | Final/OT | W | 4 |
| 4 | 2021-11-22 | Texas State (221) | 57 | 83 | Texas Tech (99) | Final | W | 26 |
| 5 | 2021-11-26 | Texas Tech (26) | 71 | 67 | Ball State (69) | Final | W | 4 |
| 6 | 2021-11-27 | Old Dominion (176) | 59 | 45 | Texas Tech (35) | Final | L | -14 |
| 7 | 2021-11-28 | Texas Tech (35) | 82 | 75 | New Mexico (154) | Final | W | 7 |
| 8 | 2021-12-02 | Georgia (5) | 66 | 56 | Texas Tech (61) | Final | L | -10 |
| 9 | 2021-12-12 | UNLV (96) | 61 | 68 | Texas Tech (66) | Final | W | 7 |
| 10 | 2021-12-20 | Texas Tech (55) | 50 | 65 | Ole Miss (44) | Final | L | -15 |
| 11 | 2021-12-21 | LSU (13) | 74 | 60 | Texas Tech (65) | Final | L | -14 |
| 12 | 2021-12-29 | Incarnate Word (275) | 0 | 0 | Texas Tech (72) | Postponed | - | - |
| 13 | 2022-01-02 | Oklahoma (10) | 97 | 91 | Texas Tech (26) | Final | L | -6 |
| 14 | 2022-01-05 | Texas Tech (26) | 74 | 61 | Texas (4) | Final | W | 13 |
| 15 | 2022-01-08 | Oklahoma State (32) | 57 | 55 | Texas Tech (26) | Final | L | -2 |
| 16 | 2022-01-12 | Texas Tech (26) | 53 | 64 | West Virginia (15) | Final | L | -11 |
| 17 | 2022-01-15 | Kansas State (11) | 45 | 64 | Texas Tech (66) | Final | W | 19 |
| 18 | 2022-01-19 | Texas Tech (26) | 50 | 51 | TCU (12) | Final | L | -1 |
| 19 | 2022-01-22 | Texas Tech (59) | 57 | 71 | Kansas (26) | Final | L | -14 |
| 20 | 2022-01-26 | Baylor (20) | 88 | 80 | Texas Tech (71) | Final | L | -8 |
| 21 | 2022-01-29 | Iowa State (8) | 86 | 65 | Texas Tech (71) | Final | L | -21 |
| 22 | 2022-02-05 | Texas Tech (26) | 75 | 82 | Kansas State (62) | Final | L | -7 |
| 23 | 2022-02-09 | Texas (4) | 61 | 56 | Texas Tech (26) | Final | L | -5 |
| 24 | 2022-02-12 | Texas Tech (77) | 58 | 62 | Oklahoma State (104) | Final | L | -4 |
| 25 | 2022-02-16 | Texas Tech (26) | 97 | 87 | Oklahoma (10) | Final | W | 10 |
| 26 | 2022-02-19 | Kansas (23) | 71 | 68 | Texas Tech (83) | Final | L | -3 |
| 27 | 2022-02-23 | West Virginia (69) | 73 | 62 | Texas Tech (77) | Final | L | -11 |
| 28 | 2022-02-26 | Texas Tech (77) | 55 | 71 | Iowa State (5) | Final | L | -16 |
| 29 | 2022-03-02 | TCU (141) | 79 | 83 | Texas Tech (80) | Final | W | 4 |
| 30 | 2022-03-06 | Texas Tech (80) | 57 | 82 | Baylor (5) | Final | L | -25 |
| 31 | 2022-03-10 | Oklahoma State (94) | 73 | 58 | Texas Tech (80) | Final | L | -15 |