NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | St. Francis (PA) (185) | 53 | 73 | Temple (112) | Final | L | -20 |
| 2 | 2021-11-14 | St. Francis (PA) (185) | 45 | 71 | Kent State (141) | Final | L | -26 |
| 3 | 2021-11-16 | St. Francis (PA) (321) | 33 | 86 | West Virginia (183) | Final | L | -53 |
| 4 | 2021-11-20 | Longwood (266) | 63 | 54 | St. Francis (PA) (321) | Final | L | -9 |
| 5 | 2021-11-28 | St. Francis (PA) (332) | 38 | 68 | Coppin State (131) | Final | L | -30 |
| 6 | 2021-12-01 | St. Francis (PA) (329) | 31 | 68 | Bucknell (131) | Final | L | -37 |
| 7 | 2021-12-08 | St. Francis (PA) (337) | 33 | 86 | Toledo (148) | Final | L | -53 |
| 8 | 2021-12-11 | St. Francis (PA) (337) | 61 | 70 | Duquesne (202) | Final | L | -9 |
| 9 | 2021-12-21 | St. Francis (PA) (345) | 43 | 60 | Jacksonville State (160) | Final | L | -17 |
| 10 | 2021-12-29 | St. Francis (PA) (346) | 56 | 65 | Wagner (162) | Final | L | -9 |
| 11 | 2022-01-06 | St. Francis (NY) (241) | 70 | 60 | St. Francis (PA) (346) | Final | L | -10 |
| 12 | 2022-01-15 | Merrimack (309) | 62 | 70 | St. Francis (PA) (338) | Final | W | 8 |
| 13 | 2022-01-17 | Bryant (317) | 62 | 70 | St. Francis (PA) (338) | Final | W | 8 |
| 14 | 2022-01-21 | St. Francis (PA) (321) | 69 | 59 | Central Connecticut State (329) | Final | W | 10 |
| 15 | 2022-01-29 | St. Francis (PA) (308) | 70 | 58 | Mount St Mary's (249) | Final | W | 12 |
| 16 | 2022-02-03 | St. Francis (PA) (302) | 36 | 58 | Bryant (332) | Final | L | -22 |
| 17 | 2022-02-11 | Fairleigh Dickinson (204) | 56 | 70 | St. Francis (PA) (315) | Final | W | 14 |
| 18 | 2022-02-17 | St. Francis (PA) (303) | 62 | 69 | Long Island (310) | Final/OT | L | -7 |
| 19 | 2022-02-19 | St. Francis (PA) (303) | 54 | 57 | St. Francis (NY) (205) | Final/OT | L | -3 |
| 20 | 2022-02-24 | Central Connecticut State (328) | 58 | 55 | St. Francis (PA) (309) | Final | L | -3 |
| 21 | 2022-02-26 | Sacred Heart (301) | 68 | 74 | St. Francis (PA) (309) | Final | W | 6 |
| 22 | 2022-03-03 | Mount St Mary's (257) | 61 | 48 | St. Francis (PA) (308) | Final | L | -13 |
| 23 | 2022-03-07 | St. Francis (PA) (308) | 53 | 69 | Mount St Mary's (257) | Final | L | -16 |