Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-01 | South Carolina (89) | 13 | Vanderbilt (76) | 10 | Final | W | 3 |
| 2 | 2016-09-10 | South Carolina | 14 | Mississippi State | 27 | Final | L | -13 |
| 3 | 2016-09-17 | East Carolina (79) | 15 | South Carolina (89) | 20 | Final | W | 5 |
| 4 | 2016-09-24 | South Carolina (44) | 10 | Kentucky (87) | 17 | Final | L | -7 |
| 5 | 2016-10-01 | Texas A&M (4) | 24 | South Carolina (68) | 13 | Final | L | -11 |
| 6 | 2016-10-09 | Georgia (47) | 28 | South Carolina (71) | 14 | Final | L | -14 |
| 7 | 2016-10-22 | Massachusetts | 28 | South Carolina | 34 | Final | W | 6 |
| 8 | 2016-10-29 | Tennessee (13) | 21 | South Carolina (83) | 24 | Final | W | 3 |
| 9 | 2016-11-05 | Missouri (90) | 21 | South Carolina (65) | 31 | Final | W | 10 |
| 10 | 2016-11-12 | South Carolina (61) | 7 | Florida (25) | 20 | Final | L | -13 |
| 11 | 2016-11-19 | Western Carolina | 31 | South Carolina | 44 | Final | W | 13 |
| 12 | 2016-11-26 | South Carolina (63) | 7 | Clemson (4) | 56 | Final | L | -49 |
| 13 | 2016-12-29 | South Florida | 46 | South Carolina | 39 | Final/OT | L | -7 |