Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-01 | Appalachian State | 13 | Tennessee | 20 | Final/OT | W | 7 |
| 2 | 2016-09-10 | Virginia Tech (54) | 24 | Tennessee (18) | 45 | Final | W | 21 |
| 3 | 2016-09-17 | Ohio (63) | 19 | Tennessee (18) | 28 | Final | W | 9 |
| 4 | 2016-09-24 | Florida (10) | 28 | Tennessee (12) | 38 | Final | W | 10 |
| 5 | 2016-10-01 | Tennessee (3) | 34 | Georgia (47) | 31 | Final | W | 3 |
| 6 | 2016-10-08 | Tennessee (3) | 38 | Texas A&M (4) | 45 | Final/2OT | L | -7 |
| 7 | 2016-10-15 | Alabama (5) | 49 | Tennessee (7) | 10 | Final | L | -39 |
| 8 | 2016-10-29 | Tennessee (13) | 21 | South Carolina (83) | 24 | Final | L | -3 |
| 9 | 2016-11-05 | Tennessee Tech | 0 | Tennessee | 55 | Final | W | 55 |
| 10 | 2016-11-12 | Kentucky (51) | 36 | Tennessee (17) | 49 | Final | W | 13 |
| 11 | 2016-11-19 | Missouri (81) | 37 | Tennessee (22) | 63 | Final | W | 26 |
| 12 | 2016-11-26 | Tennessee (18) | 34 | Vanderbilt (60) | 45 | Final | L | -11 |
| 13 | 2016-12-30 | Nebraska (20) | 24 | Tennessee (24) | 38 | Final | W | 14 |