Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-01 | Charlotte (125) | 14 | Louisville (39) | 70 | Final | L | -56 |
| 2 | 2016-09-10 | Elon | 14 | Charlotte | 47 | Final | W | 33 |
| 3 | 2016-09-17 | Eastern Michigan | 37 | Charlotte | 19 | Final | L | -18 |
| 4 | 2016-09-24 | Charlotte (105) | 20 | Temple (99) | 48 | Final | L | -28 |
| 5 | 2016-10-01 | Old Dominion (94) | 52 | Charlotte (118) | 17 | Final | L | -35 |
| 6 | 2016-10-09 | Charlotte | 28 | Florida Atlantic | 23 | Final | W | 5 |
| 7 | 2016-10-15 | Florida International | 27 | Charlotte | 26 | Final | L | -1 |
| 8 | 2016-10-22 | Charlotte (117) | 27 | Marshall (110) | 24 | Final | W | 3 |
| 9 | 2016-11-05 | Charlotte (122) | 38 | Southern Miss (63) | 27 | Final | W | 11 |
| 10 | 2016-11-12 | Rice (157) | 22 | Charlotte (102) | 21 | Final | L | -1 |
| 11 | 2016-11-19 | Middle Tennessee | 38 | Charlotte | 31 | Final | L | -7 |
| 12 | 2016-11-26 | Charlotte (116) | 14 | UTSA (87) | 33 | Final | L | -19 |