Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-03 | Alabama A&M | 0 | Middle Tennessee | 55 | Final | W | 55 |
| 2 | 2016-09-10 | Middle Tennessee | 24 | Vanderbilt | 47 | Final | L | -23 |
| 3 | 2016-09-17 | Middle Tennessee | 41 | Bowling Green | 21 | Final | W | 20 |
| 4 | 2016-09-24 | Louisiana Tech | 34 | Middle Tennessee | 38 | Final | W | 4 |
| 5 | 2016-10-01 | Middle Tennessee | 30 | North Texas | 13 | Final | W | 17 |
| 6 | 2016-10-15 | Western Kentucky | 44 | Middle Tennessee | 43 | Final/2OT | L | -1 |
| 7 | 2016-10-22 | Middle Tennessee | 51 | Missouri | 45 | Final | W | 6 |
| 8 | 2016-10-29 | Middle Tennessee | 42 | Florida International | 35 | Final | W | 7 |
| 9 | 2016-11-05 | UTSA | 45 | Middle Tennessee | 25 | Final | L | -20 |
| 10 | 2016-11-12 | Middle Tennessee | 17 | Marshall | 42 | Final | L | -25 |
| 11 | 2016-11-19 | Middle Tennessee | 38 | Charlotte | 31 | Final | W | 7 |
| 12 | 2016-11-26 | Florida Atlantic | 56 | Middle Tennessee | 77 | Final | W | 21 |
| 13 | 2016-12-24 | Hawaii | 52 | Middle Tennessee | 35 | Final | L | -17 |