Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-01 | Rice | 14 | Western Kentucky | 46 | Final | L | -32 |
| 2 | 2016-09-10 | Rice (115) | 14 | Army (121) | 31 | Final | L | -17 |
| 3 | 2016-09-16 | Baylor (16) | 38 | Rice (115) | 10 | Final | L | -28 |
| 4 | 2016-09-24 | North Texas (103) | 42 | Rice (115) | 35 | Final/2OT | L | -7 |
| 5 | 2016-10-01 | Rice (123) | 28 | Southern Miss (35) | 44 | Final | L | -16 |
| 6 | 2016-10-15 | UTSA (91) | 14 | Rice (125) | 13 | Final | L | -1 |
| 7 | 2016-10-22 | Prairie View A&M | 44 | Rice | 65 | Final | W | 21 |
| 8 | 2016-10-29 | Rice | 16 | Louisiana Tech | 61 | Final | L | -45 |
| 9 | 2016-11-05 | Florida Atlantic | 42 | Rice | 25 | Final | L | -17 |
| 10 | 2016-11-12 | Rice (157) | 22 | Charlotte (102) | 21 | Final | W | 1 |
| 11 | 2016-11-19 | UTEP (135) | 24 | Rice (145) | 44 | Final | W | 20 |
| 12 | 2016-11-26 | Rice (135) | 17 | Stanford (22) | 41 | Final | L | -24 |