Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Arkansas-Pine Bluff (303) | 57 | 99 | Marquette (106) | Final | W | 42 |
| 2 | 2020-11-27 | Eastern Illinois (314) | 50 | 75 | Marquette (106) | Final | W | 25 |
| 3 | 2020-12-01 | Oklahoma State (57) | 70 | 62 | Marquette (106) | Final | L | -8 |
| 4 | 2020-12-04 | Wisconsin (24) | 65 | 67 | Marquette (106) | Final | W | 2 |
| 5 | 2020-12-08 | Green Bay (206) | 68 | 82 | Marquette (106) | Final | W | 14 |
| 6 | 2020-12-11 | Marquette (106) | 60 | 69 | UCLA (30) | Final | L | -9 |
| 7 | 2020-12-14 | Marquette (106) | 89 | 84 | Creighton (78) | Final | W | 5 |
| 8 | 2020-12-17 | Seton Hall (53) | 70 | 63 | Marquette (106) | Final | L | -7 |
| 9 | 2020-12-20 | Marquette (106) | 88 | 91 | Xavier (92) | Final | L | -3 |
| 10 | 2020-12-23 | Villanova (29) | 85 | 68 | Marquette (106) | Final | L | -17 |
| 11 | 2021-01-02 | Marquette (106) | 64 | 60 | Georgetown (83) | Final | W | 4 |
| 12 | 2021-01-05 | Connecticut (4) | 65 | 54 | Marquette (106) | Final | L | -11 |
| 13 | 2021-01-08 | Marquette (106) | 0 | 0 | Villanova (29) | Postponed | - | - |
| 14 | 2021-01-12 | Providence (82) | 69 | 79 | Marquette (106) | Final | W | 10 |
| 15 | 2021-01-16 | Marquette (106) | 73 | 71 | St. John's (12) | Final | W | 2 |
| 16 | 2021-01-20 | Georgetown (83) | 0 | 0 | Marquette (106) | Cancelled | - | - |
| 17 | 2021-01-23 | DePaul (95) | 68 | 61 | Marquette (106) | Final | L | -7 |
| 18 | 2021-01-27 | Marquette (106) | 63 | 72 | Providence (82) | Final/OT | L | -9 |
| 19 | 2021-01-31 | St. John's (12) | 75 | 73 | Marquette (106) | Final | L | -2 |
| 20 | 2021-02-02 | Butler (80) | 67 | 70 | Marquette (106) | Final | W | 3 |
| 21 | 2021-02-06 | Creighton (78) | 71 | 68 | Marquette (106) | Final | L | -3 |
| 22 | 2021-02-10 | Marquette (106) | 64 | 96 | Villanova (29) | Final | L | -32 |
| 23 | 2021-02-14 | Marquette (106) | 51 | 57 | Seton Hall (53) | Final | L | -6 |
| 24 | 2021-02-17 | Marquette (106) | 73 | 57 | Butler (80) | Final | W | 16 |
| 25 | 2021-02-24 | Marquette (106) | 83 | 70 | North Carolina (22) | Final | W | 13 |
| 26 | 2021-02-27 | Marquette (106) | 62 | 80 | Connecticut (4) | Final | L | -18 |
| 27 | 2021-03-02 | Marquette (106) | 77 | 71 | DePaul (95) | Final | W | 6 |
| 28 | 2021-03-06 | Xavier (92) | 59 | 66 | Marquette (106) | Final | W | 7 |
| 29 | 2021-03-10 | Marquette (79) | 49 | 68 | Georgetown (93) | Final | L | -19 |