Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-28 | Chicago State (351) | 0 | 0 | DePaul (95) | Cancelled | - | - |
| 2 | 2020-12-06 | DePaul (95) | 0 | 0 | Iowa State (7) | Cancelled | - | - |
| 3 | 2020-12-11 | DePaul (170) | Deprecated: htmlspecialchars(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/allmysportsteamssuck.com/ncaa-college-basketball-schedule/index.php on line 160 |
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Seton Hall (132) | Cancelled | - | - |
| 4 | 2020-12-14 | DePaul (95) | 0 | 0 | Villanova (29) | Postponed | - | - |
| 5 | 2020-12-17 | DePaul (95) | 0 | 0 | Providence (82) | Postponed | - | - |
| 6 | 2020-12-18 | Xavier (92) | 0 | 0 | DePaul (95) | Cancelled | - | - |
| 7 | 2020-12-21 | DePaul (180) | 0 | 0 | Butler (152) | Cancelled | - | - |
| 8 | 2020-12-23 | Connecticut (50) | 0 | 0 | DePaul (170) | Cancelled | - | - |
| 9 | 2020-12-23 | Western Illinois (362) | 72 | 91 | DePaul (95) | Final | W | 19 |
| 10 | 2020-12-27 | DePaul (95) | 90 | 95 | Providence (82) | Final/2OT | L | -5 |
| 11 | 2020-12-30 | DePaul (95) | 61 | 82 | Connecticut (4) | Final | L | -21 |
| 12 | 2021-01-02 | DePaul (95) | 0 | 0 | St. John's (12) | Postponed | - | - |
| 13 | 2021-01-05 | Villanova (29) | 0 | 0 | DePaul (95) | Cancelled | - | - |
| 14 | 2021-01-09 | Seton Hall (53) | 76 | 68 | DePaul (95) | Final | L | -8 |
| 15 | 2021-01-11 | Connecticut (4) | 60 | 53 | DePaul (95) | Final | L | -7 |
| 16 | 2021-01-13 | DePaul (95) | 0 | 0 | Georgetown (83) | Cancelled | - | - |
| 17 | 2021-01-16 | Valparaiso (156) | 58 | 77 | DePaul (95) | Final | W | 19 |
| 18 | 2021-01-19 | Butler (80) | 67 | 53 | DePaul (95) | Final | L | -14 |
| 19 | 2021-01-23 | DePaul (95) | 68 | 61 | Marquette (106) | Final | W | 7 |
| 20 | 2021-01-27 | St. John's (12) | 81 | 68 | DePaul (95) | Final | L | -13 |
| 21 | 2021-01-30 | Creighton (78) | 69 | 62 | DePaul (95) | Final | L | -7 |
| 22 | 2021-02-03 | Xavier (92) | 0 | 0 | DePaul (95) | Cancelled | - | - |
| 23 | 2021-02-06 | DePaul (95) | 58 | 68 | Butler (80) | Final | L | -10 |
| 24 | 2021-02-09 | DePaul (95) | 0 | 0 | Villanova (29) | Cancelled | - | - |
| 25 | 2021-02-11 | DePaul (95) | 0 | 0 | Xavier (92) | Postponed | - | - |
| 26 | 2021-02-13 | Providence (82) | 57 | 47 | DePaul (95) | Final | L | -10 |
| 27 | 2021-02-17 | DePaul (95) | 52 | 60 | Seton Hall (53) | Final | L | -8 |
| 28 | 2021-02-20 | DePaul (95) | 88 | 83 | St. John's (12) | Final | W | 5 |
| 29 | 2021-02-24 | DePaul (95) | 53 | 77 | Creighton (78) | Final | L | -24 |
| 30 | 2021-02-27 | Georgetown (83) | 68 | 60 | DePaul (95) | Final | L | -8 |
| 31 | 2021-03-02 | Marquette (106) | 77 | 71 | DePaul (95) | Final | L | -6 |
| 32 | 2021-03-10 | DePaul (181) | 70 | 62 | Providence (72) | Final | W | 8 |
| 33 | 2021-03-11 | DePaul (95) | 60 | 94 | Connecticut (4) | Final | L | -34 |