NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Central Connecticut State (305) | 50 | 87 | Massachusetts (86) | Final | L | -37 |
| 2 | 2021-11-13 | Quinnipiac (159) | 79 | 50 | Central Connecticut State (305) | Final | L | -29 |
| 3 | 2021-11-18 | Central Connecticut State (363) | 67 | 60 | Brown (125) | Final | W | 7 |
| 4 | 2021-11-21 | NJIT (211) | 67 | 63 | Central Connecticut State (333) | Final | L | -4 |
| 5 | 2021-11-24 | Central Connecticut State (304) | 63 | 70 | UMass-Lowell (283) | Final | L | -7 |
| 6 | 2021-12-05 | Central Connecticut State (319) | 65 | 116 | Syracuse (147) | Final | L | -51 |
| 7 | 2021-12-14 | Central Connecticut State (314) | 45 | 56 | Rutgers (157) | Final | L | -11 |
| 8 | 2021-12-17 | Hartford (350) | 50 | 73 | Central Connecticut State (317) | Final | W | 23 |
| 9 | 2021-12-21 | Central Connecticut State (307) | 52 | 65 | Albany (216) | Final | L | -13 |
| 10 | 2021-12-29 | Central Connecticut State (314) | 53 | 60 | Bryant (333) | Final | L | -7 |
| 11 | 2021-12-31 | St. Francis (NY) (252) | 0 | 2 | Central Connecticut State (363) | Forfeit | W | 2 |
| 12 | 2022-01-06 | Central Connecticut State (323) | 0 | 0 | Sacred Heart (227) | Forfeit | - | - |
| 13 | 2022-01-08 | Central Connecticut State (363) | 69 | 53 | Merrimack (224) | Final | W | 16 |
| 14 | 2022-01-15 | Long Island (348) | 62 | 51 | Central Connecticut State (310) | Final | L | -11 |
| 15 | 2022-01-17 | Sacred Heart (238) | 63 | 56 | Central Connecticut State (310) | Final | L | -7 |
| 16 | 2022-01-21 | St. Francis (PA) (321) | 69 | 59 | Central Connecticut State (329) | Final | L | -10 |
| 17 | 2022-01-23 | Mount St Mary's (270) | 71 | 60 | Central Connecticut State (363) | Final | L | -11 |
| 18 | 2022-01-27 | Central Connecticut State (363) | 67 | 74 | Long Island (265) | Final | L | -7 |
| 19 | 2022-01-30 | Fairleigh Dickinson (228) | 62 | 42 | Central Connecticut State (332) | Final | L | -20 |
| 20 | 2022-02-03 | Central Connecticut State (333) | 62 | 78 | Wagner (240) | Final | L | -16 |
| 21 | 2022-02-05 | Central Connecticut State (363) | 35 | 72 | Fairleigh Dickinson (105) | Final | L | -37 |
| 22 | 2022-02-11 | Merrimack (302) | 66 | 75 | Central Connecticut State (338) | Final | W | 9 |
| 23 | 2022-02-17 | Bryant (320) | 63 | 76 | Central Connecticut State (335) | Final | W | 13 |
| 24 | 2022-02-19 | Wagner (240) | 65 | 58 | Central Connecticut State (335) | Final | L | -7 |
| 25 | 2022-02-24 | Central Connecticut State (328) | 58 | 55 | St. Francis (PA) (309) | Final | W | 3 |
| 26 | 2022-02-26 | Central Connecticut State (328) | 47 | 64 | Mount St Mary's (263) | Final | L | -17 |
| 27 | 2022-03-03 | Central Connecticut State (328) | 62 | 71 | St. Francis (NY) (214) | Final | L | -9 |
| 28 | 2022-03-05 | Central Connecticut State (328) | 58 | 62 | Sacred Heart (310) | Final | L | -4 |