NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Mobile | 59 | 63 | South Alabama (240) | Final | W | 4 |
| 2 | 2021-11-12 | South Alabama (194) | 45 | 64 | Rutgers (158) | Final | L | -19 |
| 3 | 2021-11-15 | Auburn-Montgomery | 49 | 70 | South Alabama (240) | Final | W | 21 |
| 4 | 2021-11-20 | South Alabama (265) | 53 | 86 | Tulane (55) | Final | L | -33 |
| 5 | 2021-11-23 | New Orleans (356) | 53 | 63 | South Alabama (194) | Final | W | 10 |
| 6 | 2021-11-26 | Mercer (245) | 67 | 53 | South Alabama (194) | Final | L | -14 |
| 7 | 2021-11-28 | South Alabama (287) | 59 | 69 | Alabama State (322) | Final | L | -10 |
| 8 | 2021-12-05 | Southern Miss (232) | 71 | 51 | South Alabama (308) | Final | L | -20 |
| 9 | 2021-12-11 | South Alabama (324) | 73 | 63 | Nicholls State (334) | Final | W | 10 |
| 10 | 2021-12-14 | Faulkner | 51 | 91 | South Alabama (309) | Final | W | 40 |
| 11 | 2021-12-18 | South Alabama (194) | 52 | 51 | Charleston Southern (317) | Final | W | 1 |
| 12 | 2021-12-19 | Tulsa (140) | 92 | 62 | South Alabama (194) | Final | L | -30 |
| 13 | 2021-12-21 | South Alabama (303) | 50 | 89 | Georgia (10) | Final | L | -39 |
| 14 | 2021-12-30 | Appalachian State (255) | 0 | 0 | South Alabama (305) | Cancelled | - | - |
| 15 | 2022-01-01 | Coastal Carolina (115) | 0 | 0 | South Alabama (305) | Canceled | - | - |
| 16 | 2022-01-06 | South Alabama (309) | 0 | 0 | Texas-Arlington (73) | Canceled | - | - |
| 17 | 2022-01-08 | South Alabama (194) | 0 | 0 | Texas State (255) | Canceled | - | - |
| 18 | 2022-01-13 | South Alabama (194) | 69 | 54 | Louisiana-Monroe (169) | Final | W | 15 |
| 19 | 2022-01-15 | Louisiana (129) | 71 | 64 | South Alabama (308) | Final | L | -7 |
| 20 | 2022-01-20 | Arkansas State (204) | 65 | 73 | South Alabama (298) | Final | W | 8 |
| 21 | 2022-01-22 | Little Rock (138) | 74 | 52 | South Alabama (298) | Final | L | -22 |
| 22 | 2022-01-27 | South Alabama (194) | 66 | 72 | Georgia State (250) | Final/OT | L | -6 |
| 23 | 2022-01-29 | South Alabama (297) | 69 | 77 | Georgia Southern (170) | Final | L | -8 |
| 24 | 2022-02-05 | South Alabama (194) | 52 | 84 | Troy (67) | Final | L | -32 |
| 25 | 2022-02-12 | Troy (100) | 80 | 60 | South Alabama (309) | Final | L | -20 |
| 26 | 2022-02-17 | Georgia Southern (164) | 68 | 56 | South Alabama (305) | Final | L | -12 |
| 27 | 2022-02-19 | Georgia State (282) | 60 | 57 | South Alabama (305) | Final/OT | L | -3 |
| 28 | 2022-02-24 | South Alabama (311) | 62 | 79 | Coastal Carolina (208) | Final | L | -17 |
| 29 | 2022-02-26 | South Alabama (311) | 50 | 72 | Appalachian State (199) | Final | L | -22 |
| 30 | 2022-03-02 | South Alabama (316) | 66 | 80 | Texas State (207) | Final | L | -14 |