NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-10 | Saint Mary's (224) | 66 | 61 | Nevada (176) | Final | W | 5 |
| 2 | 2021-11-13 | Saint Mary's (224) | 52 | 50 | UC-Davis (61) | Final | W | 2 |
| 3 | 2021-11-16 | Saint Mary's (79) | 50 | 92 | Utah (44) | Final | L | -42 |
| 4 | 2021-11-20 | Western Michigan (228) | 76 | 67 | Saint Mary's (79) | Final/OT | L | -9 |
| 5 | 2021-11-26 | TCU (12) | 72 | 68 | Saint Mary's (223) | Final | L | -4 |
| 6 | 2021-11-27 | UC-Santa Barbara (132) | 45 | 68 | Saint Mary's (218) | Final | W | 23 |
| 7 | 2021-11-30 | San Jose State (254) | 71 | 79 | Saint Mary's (168) | Final | W | 8 |
| 8 | 2021-12-04 | Fresno State (208) | 69 | 81 | Saint Mary's (223) | Final | W | 12 |
| 9 | 2021-12-12 | Saint Mary's (137) | 73 | 101 | North Carolina State (2) | Final | L | -28 |
| 10 | 2021-12-15 | Saint Mary's (114) | 61 | 58 | Coastal Carolina (103) | Final | W | 3 |
| 11 | 2021-12-21 | Saint Mary's (121) | 55 | 73 | California (80) | Final | L | -18 |
| 12 | 2021-12-30 | Saint Mary's (132) | 0 | 0 | Santa Clara (150) | Postponed | - | - |
| 13 | 2022-01-01 | Saint Mary's (132) | 0 | 0 | Pepperdine (220) | Postponed | - | - |
| 14 | 2022-01-06 | Loyola Marymount (217) | 0 | 0 | Saint Mary's (126) | Postponed | - | - |
| 15 | 2022-01-08 | Portland (138) | 0 | 0 | Saint Mary's (223) | Postponed | - | - |
| 16 | 2022-01-11 | Loyola Marymount (222) | 63 | 82 | Saint Mary's (130) | Final | W | 19 |
| 17 | 2022-01-13 | Saint Mary's (223) | 36 | 78 | BYU (45) | Final | L | -42 |
| 18 | 2022-01-15 | Pepperdine (228) | 53 | 70 | Saint Mary's (130) | Final | W | 17 |
| 19 | 2022-01-20 | Saint Mary's (127) | 79 | 71 | San Diego (84) | Final | W | 8 |
| 20 | 2022-01-22 | Gonzaga (41) | 66 | 53 | Saint Mary's (127) | Final | L | -13 |
| 21 | 2022-01-27 | San Francisco (152) | 70 | 56 | Saint Mary's (223) | Final | L | -14 |
| 22 | 2022-01-29 | Saint Mary's (117) | 62 | 73 | Loyola Marymount (258) | Final | L | -11 |
| 23 | 2022-01-31 | Saint Mary's (223) | 65 | 70 | Pepperdine (146) | Final/OT | L | -5 |
| 24 | 2022-02-03 | Santa Clara (156) | 73 | 78 | Saint Mary's (159) | Final | W | 5 |
| 25 | 2022-02-05 | Saint Mary's (223) | 96 | 80 | Pacific (227) | Final | W | 16 |
| 26 | 2022-02-07 | Saint Mary's (223) | 88 | 81 | Santa Clara (86) | Final | W | 7 |
| 27 | 2022-02-10 | Saint Mary's (223) | 63 | 73 | Portland (138) | Final | L | -10 |
| 28 | 2022-02-12 | BYU (14) | 84 | 69 | Saint Mary's (147) | Final | L | -15 |
| 29 | 2022-02-17 | Saint Mary's (146) | 49 | 85 | Gonzaga (33) | Final | L | -36 |
| 30 | 2022-02-19 | San Diego (112) | 67 | 79 | Saint Mary's (146) | Final | W | 12 |
| 31 | 2022-02-21 | Portland (70) | 89 | 84 | Saint Mary's (146) | Final | L | -5 |
| 32 | 2022-02-24 | Pacific (268) | 67 | 83 | Saint Mary's (146) | Final | W | 16 |
| 33 | 2022-02-26 | Saint Mary's (146) | 92 | 88 | San Francisco (120) | Final/OT | W | 4 |
| 34 | 2022-03-04 | Loyola Marymount (240) | 71 | 64 | Saint Mary's (139) | Final | L | -7 |
| 35 | 2022-03-18 | Austin Peay (191) | 69 | 77 | Saint Mary's (149) | Final | W | 8 |
| 36 | 2022-03-19 | Saint Mary's (149) | 76 | 67 | Bowling Green (141) | Final | W | 9 |
| 37 | 2022-03-20 | Cleveland State (135) | 73 | 80 | Saint Mary's (149) | Final | W | 7 |