Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-03 | Duquesne (173) | 14 | Youngstown State (176) | 31 | Final | W | 17 |
| 2 | 2022-09-10 | Dayton (216) | 16 | Youngstown State (176) | 49 | Final | W | 33 |
| 3 | 2022-09-17 | Youngstown State (146) | 0 | Kentucky (17) | 31 | Final | L | -31 |
| 4 | 2022-10-01 | Youngstown State (167) | 14 | North Dakota State (135) | 27 | Final | L | -13 |
| 5 | 2022-10-08 | North Dakota (152) | 35 | Youngstown State (182) | 30 | Final | L | -5 |
| 6 | 2022-10-15 | Indiana State (226) | 42 | Youngstown State (178) | 48 | Final | W | 6 |
| 7 | 2022-10-22 | Youngstown State (178) | 28 | Western Illinois (249) | 27 | Final | W | 1 |
| 8 | 2022-10-29 | South Dakota (201) | 24 | Youngstown State (170) | 45 | Final | W | 21 |
| 9 | 2022-11-05 | Youngstown State (165) | 19 | Illinois State (174) | 17 | Final | W | 2 |
| 10 | 2022-11-12 | Youngstown State (171) | 22 | Missouri State (180) | 25 | Final | L | -3 |
| 11 | 2022-11-19 | Southern Illinois (169) | 21 | Youngstown State (168) | 28 | Final | W | 7 |