Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-03 | Towson (200) | 14 | Bucknell (255) | 13 | Final | W | 1 |
| 2 | 2022-09-10 | Morgan State (253) | 21 | Towson (200) | 29 | Final | W | 8 |
| 3 | 2022-09-17 | Towson (171) | 7 | West Virginia (85) | 65 | Final | L | -58 |
| 4 | 2022-09-24 | New Hampshire (156) | 37 | Towson (188) | 14 | Final | L | -23 |
| 5 | 2022-10-01 | Towson (194) | 10 | Delaware (91) | 24 | Final | L | -14 |
| 6 | 2022-10-08 | Towson (207) | 10 | Elon (125) | 27 | Final | L | -17 |
| 7 | 2022-10-22 | William & Mary (107) | 44 | Towson (210) | 24 | Final | L | -20 |
| 8 | 2022-10-29 | Towson (194) | 52 | Monmouth (193) | 48 | Final | W | 4 |
| 9 | 2022-11-05 | Villanova (184) | 3 | Towson (182) | 27 | Final | W | 24 |
| 10 | 2022-11-12 | Towson (177) | 21 | Stony Brook (223) | 17 | Final | W | 4 |
| 11 | 2022-11-19 | Hampton (212) | 7 | Towson (174) | 27 | Final | W | 20 |