Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-01 | Tulane (122) | 3 | Wake Forest (90) | 7 | Final | W | 4 |
| 2 | 2016-09-10 | Wake Forest (90) | 24 | Duke (58) | 14 | Final | W | 10 |
| 3 | 2016-09-17 | Delaware | 21 | Wake Forest | 38 | Final | W | 17 |
| 4 | 2016-09-24 | Wake Forest (31) | 33 | Indiana (27) | 28 | Final | W | 5 |
| 5 | 2016-10-01 | Wake Forest | 16 | North Carolina State | 33 | Final | L | -17 |
| 6 | 2016-10-08 | Syracuse (95) | 9 | Wake Forest (28) | 28 | Final | W | 19 |
| 7 | 2016-10-15 | Wake Forest (22) | 6 | Florida State (21) | 17 | Final | L | -11 |
| 8 | 2016-10-29 | Army (80) | 21 | Wake Forest (44) | 13 | Final | L | -8 |
| 9 | 2016-11-05 | Virginia (109) | 20 | Wake Forest (56) | 27 | Final | W | 7 |
| 10 | 2016-11-12 | Wake Forest (60) | 12 | Louisville (6) | 44 | Final | L | -32 |
| 11 | 2016-11-19 | Clemson (4) | 35 | Wake Forest (62) | 13 | Final | L | -22 |
| 12 | 2016-11-26 | Boston College (83) | 17 | Wake Forest (66) | 14 | Final | L | -3 |
| 13 | 2016-12-27 | Temple (22) | 26 | Wake Forest (73) | 34 | Final | W | 8 |