Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-03 | Richmond | 37 | Virginia | 20 | Final | L | -17 |
| 2 | 2016-09-10 | Virginia (87) | 26 | Oregon (35) | 44 | Final | L | -18 |
| 3 | 2016-09-17 | Virginia | 10 | Connecticut | 13 | Final | L | -3 |
| 4 | 2016-09-24 | Central Michigan | 35 | Virginia | 49 | Final | W | 14 |
| 5 | 2016-10-01 | Virginia (119) | 34 | Duke (85) | 20 | Final | W | 14 |
| 6 | 2016-10-15 | Pittsburgh | 45 | Virginia | 31 | Final | L | -14 |
| 7 | 2016-10-22 | North Carolina (33) | 35 | Virginia (104) | 14 | Final | L | -21 |
| 8 | 2016-10-29 | Louisville (7) | 32 | Virginia (110) | 25 | Final | L | -7 |
| 9 | 2016-11-05 | Virginia (109) | 20 | Wake Forest (56) | 27 | Final | L | -7 |
| 10 | 2016-11-12 | Miami (40) | 34 | Virginia (118) | 14 | Final | L | -20 |
| 11 | 2016-11-19 | Virginia (118) | 17 | Georgia Tech (48) | 31 | Final | L | -14 |
| 12 | 2016-11-26 | Virginia (122) | 10 | Virginia Tech (28) | 52 | Final | L | -42 |