Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-09-04 | Utah State | 26 | Washington State | 23 | Final | W | 3 |
| 2 | 2021-09-10 | North Dakota | 24 | Utah State | 48 | Final | W | 24 |
| 3 | 2021-09-18 | Utah State | 49 | Air Force | 45 | Final | W | 4 |
| 4 | 2021-09-25 | Boise State | 27 | Utah State | 3 | Final | L | -24 |
| 5 | 2021-10-01 | BYU | 34 | Utah State | 20 | Final | L | -14 |
| 6 | 2021-10-16 | Utah State | 28 | UNLV | 24 | Final | W | 4 |
| 7 | 2021-10-22 | Colorado State | 24 | Utah State | 26 | Final | W | 2 |
| 8 | 2021-10-30 | Hawaii | 31 | Utah State | 45 | Final | W | 14 |
| 9 | 2021-11-06 | Utah State | 35 | New Mexico State | 13 | Final | W | 22 |
| 10 | 2021-11-13 | Utah State | 48 | San Jose State | 17 | Final | W | 31 |
| 11 | 2021-11-20 | Wyoming | 44 | Utah State | 17 | Final | L | -27 |
| 12 | 2021-11-26 | Utah State (46) | 35 | New Mexico (137) | 10 | Final | W | 25 |
| 13 | 2021-12-04 | Utah State (38) | 46 | San Diego State (23) | 13 | Final | W | 33 |
| 14 | 2021-12-18 | Utah State (35) | 24 | Oregon State (66) | 13 | Final | W | 11 |