Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-03 | Louisiana Tech | 20 | Arkansas | 21 | Final | L | -1 |
| 2 | 2016-09-10 | South Carolina State | 24 | Louisiana Tech | 53 | Final | W | 29 |
| 3 | 2016-09-17 | Louisiana Tech | 45 | Texas Tech | 59 | Final | L | -14 |
| 4 | 2016-09-24 | Louisiana Tech | 34 | Middle Tennessee | 38 | Final | L | -4 |
| 5 | 2016-10-01 | UTEP | 7 | Louisiana Tech | 28 | Final | W | 21 |
| 6 | 2016-10-06 | Western Kentucky | 52 | Louisiana Tech | 55 | Final | W | 3 |
| 7 | 2016-10-15 | Louisiana Tech | 56 | Massachusetts | 28 | Final | W | 28 |
| 8 | 2016-10-22 | Louisiana Tech | 44 | Florida International | 24 | Final | W | 20 |
| 9 | 2016-10-29 | Rice | 16 | Louisiana Tech | 61 | Final | W | 45 |
| 10 | 2016-11-05 | Louisiana Tech | 45 | North Texas | 24 | Final | W | 21 |
| 11 | 2016-11-12 | UTSA | 35 | Louisiana Tech | 63 | Final | W | 28 |
| 12 | 2016-11-25 | Louisiana Tech | 24 | Southern Miss | 39 | Final | L | -15 |
| 13 | 2016-12-03 | Louisiana Tech | 44 | Western Kentucky | 58 | Final | L | -14 |
| 14 | 2016-12-23 | Louisiana Tech | 48 | Navy | 45 | Final | W | 3 |