Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-09-04 | Montana | 13 | Washington | 7 | Final | W | 6 |
| 2 | 2021-09-11 | Western Illinois | 7 | Montana | 42 | Final | W | 35 |
| 3 | 2021-09-25 | Cal Poly | 7 | Montana | 39 | Final | W | 32 |
| 4 | 2021-10-02 | Montana | 28 | Eastern Washington | 34 | Final | L | -6 |
| 5 | 2021-10-09 | Dixie State | 14 | Montana | 31 | Final | W | 17 |
| 6 | 2021-10-16 | Sacramento State | 28 | Montana | 27 | Final | L | -1 |
| 7 | 2021-10-23 | Montana | 34 | Idaho | 14 | Final | W | 20 |
| 8 | 2021-10-30 | Southern Utah | 19 | Montana | 20 | Final | W | 1 |
| 9 | 2021-11-06 | Montana | 35 | Northern Colorado | 0 | Final | W | 35 |
| 10 | 2021-11-13 | Montana | 30 | Northern Arizona | 3 | Final | W | 27 |
| 11 | 2021-11-20 | Montana State | 10 | Montana | 29 | Final | W | 19 |
| 12 | 2021-12-03 | Eastern Washington (112) | 41 | Montana (99) | 57 | Final | W | 16 |
| 13 | 2021-12-10 | Montana (99) | 6 | James Madison (89) | 28 | Final | L | -22 |