Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-08-28 | Southern Utah | 14 | San Jose State | 45 | Final | L | -31 |
| 2 | 2021-09-02 | Southern Utah | 14 | Arizona State | 41 | Final | L | -27 |
| 3 | 2021-09-18 | Southern Utah | 40 | Tarleton State | 35 | Final | W | 5 |
| 4 | 2021-09-25 | Eastern Washington | 50 | Southern Utah | 21 | Final | L | -29 |
| 5 | 2021-10-02 | Portland State | 20 | Southern Utah | 13 | Final | L | -7 |
| 6 | 2021-10-09 | Southern Utah | 20 | Sacramento State | 41 | Final | L | -21 |
| 7 | 2021-10-16 | Southern Utah | 35 | Northern Arizona | 59 | Final | L | -24 |
| 8 | 2021-10-23 | Northern Colorado | 17 | Southern Utah | 9 | Final | L | -8 |
| 9 | 2021-10-30 | Southern Utah | 19 | Montana | 20 | Final | L | -1 |
| 10 | 2021-11-06 | Southern Utah | 24 | Idaho | 42 | Final | L | -18 |
| 11 | 2021-11-13 | Weber State | 62 | Southern Utah | 0 | Final | L | -62 |