Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-03 | Southeast Missouri State | 17 | Memphis | 35 | Final | W | 18 |
| 2 | 2016-09-17 | Kansas (126) | 7 | Memphis (25) | 43 | Final | W | 36 |
| 3 | 2016-09-24 | Bowling Green (113) | 3 | Memphis (36) | 77 | Final | W | 74 |
| 4 | 2016-10-01 | Memphis (19) | 28 | Ole Miss (48) | 48 | Final | L | -20 |
| 5 | 2016-10-06 | Temple (73) | 27 | Memphis (32) | 34 | Final | W | 7 |
| 6 | 2016-10-14 | Memphis (23) | 24 | Tulane (62) | 14 | Final | W | 10 |
| 7 | 2016-10-22 | Memphis (29) | 28 | Navy (31) | 42 | Final | L | -14 |
| 8 | 2016-10-29 | Tulsa (46) | 59 | Memphis (41) | 30 | Final | L | -29 |
| 9 | 2016-11-05 | Memphis (53) | 51 | SMU (73) | 7 | Final | W | 44 |
| 10 | 2016-11-12 | South Florida | 49 | Memphis | 42 | Final | L | -7 |
| 11 | 2016-11-18 | Memphis (50) | 34 | Cincinnati (97) | 7 | Final | W | 27 |
| 12 | 2016-11-25 | Houston (16) | 44 | Memphis (44) | 48 | Final | W | 4 |
| 13 | 2016-12-20 | Memphis | 31 | Western Kentucky | 51 | Final | L | -20 |