Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-01 | Tennessee-Martin | 7 | Cincinnati | 28 | Final | W | 21 |
| 2 | 2016-09-10 | Cincinnati (64) | 38 | Purdue (99) | 20 | Final | W | 18 |
| 3 | 2016-09-15 | Houston (8) | 40 | Cincinnati (64) | 16 | Final | L | -24 |
| 4 | 2016-09-24 | Miami (OH) (127) | 20 | Cincinnati (53) | 27 | Final | W | 7 |
| 5 | 2016-10-01 | South Florida | 45 | Cincinnati | 20 | Final | L | -25 |
| 6 | 2016-10-08 | Cincinnati | 9 | Connecticut | 20 | Final | L | -11 |
| 7 | 2016-10-22 | East Carolina (92) | 19 | Cincinnati (85) | 31 | Final | W | 12 |
| 8 | 2016-10-29 | Cincinnati (82) | 13 | Temple (43) | 34 | Final | L | -21 |
| 9 | 2016-11-05 | BYU (51) | 20 | Cincinnati (86) | 3 | Final | L | -17 |
| 10 | 2016-11-12 | Cincinnati | 3 | Central Florida | 24 | Final | L | -21 |
| 11 | 2016-11-18 | Memphis (50) | 34 | Cincinnati (97) | 7 | Final | L | -27 |
| 12 | 2016-11-25 | Cincinnati (99) | 37 | Tulsa (30) | 40 | Final/OT | L | -3 |