Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-03 | Stephen F. Austin | 17 | Texas Tech | 69 | Final | W | 52 |
| 2 | 2016-09-10 | Texas Tech (59) | 55 | Arizona State (60) | 68 | Final | L | -13 |
| 3 | 2016-09-17 | Louisiana Tech | 45 | Texas Tech | 59 | Final | W | 14 |
| 4 | 2016-09-29 | Kansas (100) | 19 | Texas Tech (50) | 55 | Final | W | 36 |
| 5 | 2016-10-08 | Texas Tech (41) | 38 | Kansas State (60) | 44 | Final | L | -6 |
| 6 | 2016-10-15 | West Virginia (14) | 48 | Texas Tech (53) | 17 | Final | L | -31 |
| 7 | 2016-10-22 | Oklahoma (23) | 66 | Texas Tech (66) | 59 | Final | L | -7 |
| 8 | 2016-10-29 | Texas Tech (71) | 27 | TCU (64) | 24 | Final/2OT | W | 3 |
| 9 | 2016-11-05 | Texas (60) | 45 | Texas Tech (64) | 37 | Final | L | -8 |
| 10 | 2016-11-12 | Texas Tech (71) | 44 | Oklahoma State (33) | 45 | Final | L | -1 |
| 11 | 2016-11-19 | Texas Tech (72) | 10 | Iowa State (125) | 66 | Final | L | -56 |
| 12 | 2016-11-25 | Baylor (53) | 35 | Texas Tech (85) | 54 | Final | W | 19 |