Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-09-05 | Southern Illinois | 47 | Indiana | 48 | Final | W | 1 |
| 2 | 2015-09-12 | Florida International (108) | 22 | Indiana (89) | 36 | Final | W | 14 |
| 3 | 2015-09-19 | Western Kentucky | 35 | Indiana | 38 | Final | W | 3 |
| 4 | 2015-09-26 | Indiana (26) | 31 | Wake Forest (79) | 24 | Final | W | 7 |
| 5 | 2015-10-03 | Ohio State (9) | 34 | Indiana (25) | 27 | Final | L | -7 |
| 6 | 2015-10-10 | Indiana (34) | 7 | Penn State (37) | 29 | Final | L | -22 |
| 7 | 2015-10-17 | Rutgers (91) | 55 | Indiana (37) | 52 | Final | L | -3 |
| 8 | 2015-10-24 | Indiana (54) | 26 | Michigan State (6) | 52 | Final | L | -26 |
| 9 | 2015-11-07 | Iowa (9) | 35 | Indiana (64) | 27 | Final | L | -8 |
| 10 | 2015-11-14 | Michigan (10) | 48 | Indiana (66) | 41 | Final/2OT | L | -7 |
| 11 | 2015-11-21 | Indiana (67) | 47 | Maryland (81) | 28 | Final | W | 19 |
| 12 | 2015-11-28 | Indiana (60) | 54 | Purdue (98) | 36 | Final | W | 18 |
| 13 | 2015-12-26 | Indiana (52) | 41 | Duke (61) | 44 | Final/OT | L | -3 |