Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-09-04 | Campbell | 7 | Liberty | 48 | Final | L | -41 |
| 2 | 2021-09-11 | Elon | 24 | Campbell | 23 | Final | L | -1 |
| 3 | 2021-09-18 | Presbyterian | 0 | Campbell | 72 | Final | W | 72 |
| 4 | 2021-10-02 | Campbell | 48 | North Alabama | 31 | Final | W | 17 |
| 5 | 2021-10-09 | Campbell | 42 | Gardner-Webb | 28 | Final | W | 14 |
| 6 | 2021-10-16 | Monmouth | 34 | Campbell | 17 | Final | L | -17 |
| 7 | 2021-10-23 | Kennesaw State | 30 | Campbell | 7 | Final | L | -23 |
| 8 | 2021-10-30 | Campbell | 14 | Charleston Southern | 27 | Final | L | -13 |
| 9 | 2021-11-06 | Campbell | 14 | James Madison | 51 | Final | L | -37 |
| 10 | 2021-11-13 | Hampton | 28 | Campbell | 21 | Final | L | -7 |
| 11 | 2021-11-20 | Campbell | 17 | Robert Morris | 20 | Final(OT) | L | -3 |